Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | GALR3 | O60755 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | GPR139 | Q6DWJ6 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8504729 | 0.90 | IDO1 (0.41) | IDO1MEN1KMT2ATP53MAPT | |
| SCHEMBL8502514 | 0.87 | IDO1 (0.40) | IDO1MRGPRX4MEN1KMT2ATP53 | |
| SCHEMBL8502112 | 0.87 | IDO1 (0.40) | IDO1DOT1LCYP2C9GALR3CYP3A4 | |
| SCHEMBL8505812 | 0.86 | ADRB2 (0.42) | IDO1MEN1KMT2ATP53MAPT | |
| SCHEMBL8503797 | 0.84 | MAPK1 (0.44) | IDO1KMT2ATP53MAPTSMN1; SMN2 | |
| SCHEMBL8505637 | 0.84 | IDO1 (0.35) | IDO1MEN1KMT2ATP53MAPT | |
| SCHEMBL8505614 | 0.82 | NLRP3 (0.41) | IDO1TP53MAPTSMN1; SMN2HIF1A | |
| SCHEMBL8503177 | 0.81 | POLB (0.38) | IDO1MEN1KMT2AMAPTPOLB | |
| SCHEMBL8503700 | 0.80 | POLB (0.43) | IDO1MRGPRX4TP53MAPTDOT1L | |
| SCHEMBL8502188 | 0.79 | GAA (0.38) | IDO1MEN1KMT2ADOT1LPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5886178-A | ADMINISTERING OF A PROSTAGLANDIN G/H SYNTHASE INHIBITOR TO A PATIENT TO TREAT INFLAMMATORY OR AUTOIMMUNE DISEASES | SYNTEX (U.S.A.) INC. (US) | 1999-03-23 | — | — | US | disclosed |