Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.48 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.48 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19661172 | 1.00 | CA2 (0.56) | CA2MAPK1ALOX15BLMPMP22 | |
| SCHEMBL27674258 | 0.89 | CA2 (0.65) | CA2MAPK1ALOX15BLMPMP22 | |
| SCHEMBL28217208 | 0.85 | CA2 (0.61) | CA2MAPK1ALOX15BLMPMP22 | |
| SCHEMBL9755307 | 0.85 | CA2 (0.61) | CA2MAPK1ALOX15BLMPMP22 | |
| SCHEMBL3419778 | 0.84 | CHRM1 (0.70) | CA2MAPK1ALOX15BLMPMP22 | |
| SCHEMBL21906568 | 0.84 | CA2 (0.61) | CA2MAPK1ALOX15BLMPMP22 | |
| SCHEMBL25853764 | 0.84 | CA2 (0.61) | CA2MAPK1ALOX15BLMPMP22 | |
| SCHEMBL27562323 | 0.83 | ALOX15 (0.58) | ALOX15BLMPMP22KMT2ASLC1A1 | |
| SCHEMBL8722957 | 0.82 | CA2 (0.43) | CA2MAPK1ALOX15BLMPMP22 | |
| SCHEMBL1722576 | 0.81 | FOLH1 (0.62) | CA2MAPK1FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160058728-A1 | CANCER STARVATION THERAPY | SERBIG PHARMACEUTICALS CORP. (PR) | 2016-03-03 | — | — | US | disclosed |
| US-7442495-B2 | Photothermographic material | FUJIFILM CORPORATION (JP) | 2008-10-28 | — | — | US | disclosed |
| US-7416838-B2 | Photothermographic material | FUJIFILM CORPORATION (JP) | 2008-08-26 | — | — | US | disclosed |
| US-20080145869-A1 | Immunoassay method | FUJIFILM CORPORATION (JP) | 2008-06-19 | — | — | US | disclosed |
| US-20070207417-A1 | Photothermographic material | FUJIFILM CORPORATION | 2007-09-06 | — | — | US | disclosed |
| US-7232652-B2 | Photothermographic material and image forming method | FUJIFILM CORPORATION (JP) | 2007-06-19 | — | — | US | disclosed |
| US-5864035-A | USED FOR PHOTODYNAMIC THEARPY | HEALTH RESEARCH, INC. (US) | 1999-01-26 | — | — | US | disclosed |
| US-5770730-A | Synthesis of carbodimide analogs of chlorins and bacteriochlorins and their use for diagnosis and treatment of cancer | HEALTH RESEARCH, INC. (US) | 1998-06-23 | — | — | US | disclosed |
| WO-1997032885-A9 | SYNTHESIS OF ISOIMIDE OF CHLORINS AND BACTERIOCHLORINS AND THEIR USE FOR DIAGNOSIS AND TREATMENT OF CANCER | — | 1997-12-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160058728-A1 | CANCER STARVATION THERAPY | TUFM, TFAM, GFM1 | CA2 3665/4885MAPK1 3666/4885ALOX15 4363/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.