Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.41 |
| ▸ | MYC | P01106 | 1/20 | 0.40 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.40 |
| ▸ | IDH1 | O75874 | 1/20 | 0.39 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | OXTR | P30559 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzenesulfonamide SCHEMBL8525170 | 0.94 | PTGS1 (0.44) | ALDH1A1MEN1KMT2AGAAALOX15 | |
| SCHEMBL8505563 | 0.89 | PTGS2 (0.50) | ALDH1A1KMT2APKMHPGDFFAR4 | |
| SCHEMBL8524922 | 0.86 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2AALOX15HSD17B10 | |
| SCHEMBL8502313 | 0.84 | ALDH1A1 (0.49) | ALDH1A1MEN1KMT2AGAAPKM | |
| SCHEMBL8505150 | 0.84 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2AALOX15HSD17B10 | |
| SCHEMBL8505452 | 0.82 | HPGD (0.46) | ALDH1A1MEN1KMT2AHPGDHTT | |
| SCHEMBL8504469 | 0.82 | TSHR (0.48) | ALDH1A1MEN1KMT2AGAAPKM | |
| SCHEMBL8506102 | 0.81 | POLB (0.44) | ALDH1A1MEN1KMT2AGAAALOX15 | |
| SCHEMBL8502466 | 0.80 | CYP2C9 (0.53) | ALDH1A1MEN1KMT2AGAAPKM | |
| SCHEMBL8502558 | 0.79 | PKM (0.41) | MEN1KMT2APKMHPGDFFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5935990-A | PYRROLYL DERIVATIVES HAVING AT POSITION 1 OR 5 A PHENYL SUBSTITUTED WITH METHYLSULFONYL OR AMINOSULFONYL; INHIBIT CYCLOOXYGENASE-2 FOR USE TREATMENT OF INFLAMMATION, AS AN ANALGESIC, OR AS AN ANTIPYRETIC | G.D. SEARLE & CO. (US) | 1999-08-10 | — | — | US | disclosed |