Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6551912 | 0.85 | HSD17B10 (0.39) | NLRP3HSD17B10NPC1ALDH1A1 | |
| SCHEMBL16049982 | 0.82 | ALDH1A1 (0.39) | HSD17B10NPC1ALDH1A1GAA | |
| SCHEMBL1885025 | 0.82 | GLA (0.32) | — | |
| SCHEMBL7208632 | 0.80 | NPC1 (0.46) | NPC1ALDH1A1 | |
| SCHEMBL7278778 | 0.78 | NAAA (0.45) | HSD17B10NPC1 | |
| SCHEMBL8505753 | 0.78 | NPC1 (0.38) | NLRP3HSD17B10NPC1ALDH1A1 | |
| SCHEMBL1884135 | 0.76 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL11095324 | 0.76 | NPC1 (0.36) | NPC1ALDH1A1 | |
| SCHEMBL2099423 | 0.75 | PRKCA (0.47) | NPC1 | |
| SCHEMBL977159 | 0.75 | MAP3K14 (0.38) | NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7935686-B2 | Acyloxyalkyl carbamate prodrugs, methods of synthesis, and use | XENOPORT, INC. (US) | 2011-05-03 | — | — | US | disclosed |
| WO-2006050472-A2 | ACYLOXYALKYL CARBAMATE PRODRUGS OF 3-AMINOPROPYLPHOSPHONOUS AND -PHOSPHINIC ACIDS | XENOPORT, INC. (US) | 2006-05-11 | — | — | WO | disclosed |