SCHEMBL8508964

SCHEMBL8508964

ClCc1ccc(CCCCCCCCCC[Si](Cl)(Cl)Cl)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRA P10827 1/20 0.36
THRB P10828 1/20 0.36
HRH1 P35367 2/20 0.35
ESR1 P03372 2/20 0.35
ADRA2A P08913 2/20 0.35
ADORA3 P0DMS8 2/20 0.35
TACR2 P21452 2/20 0.35
SLC6A2 P23975 2/20 0.35
SLC6A4 P31645 2/20 0.35
SLC6A3 Q01959 2/20 0.35
KDM4E B2RXH2 1/20 0.35
ALDH1A1 P00352 1/20 0.35
LMNA P02545 1/20 0.35
SHBG P04278 1/20 0.35
TP53 P04637 1/20 0.35
CYP3A4 P08684 1/20 0.35
HSPD1 P10809 1/20 0.35
ADRB3 P13945 1/20 0.35
HTR2C P28335 1/20 0.35
HSPE1 P61604 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4298278 0.91 CA1 (0.34) THRATHRBHTR2AMAOBIGF1R
SCHEMBL926567 0.82 CA2 (0.37) ESR1CA1CA2
SCHEMBL17442485 0.82 MAOB (0.36) HRH1ESR1ADRA2AADORA3TACR2
SCHEMBL30965275 0.82 MAOB (0.44) THRATHRBESR1ADRA2AADORA3
SCHEMBL11207785 0.82 THRA (0.35) THRATHRBESR1ADRA2AADORA3
SCHEMBL5482754 0.81 SIGMAR1 (0.52) MAOBSIGMAR1
SCHEMBL18979256 0.81 SIGMAR1 (0.52) MAOBSIGMAR1
SCHEMBL574732 0.81 SIGMAR1 (0.52) MAOBSIGMAR1
SCHEMBL29118253 0.81 SIGMAR1 (0.52) MAOBSIGMAR1
SCHEMBL5488263 0.81 SIGMAR1 (0.52) MAOBSIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0561279-B1 Organic magnetic film and method of manufacturing the same MATSUSHITA ELECTRIC INDUSTRIAL CO LTD (JP) 1999-12-29 EP disclosed
US-5552236-A CHEMICAL ADSORPTION MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1996-09-03 US disclosed
EP-0561279-A1 Organic magnetic film and method of manufacturing the same MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1993-09-22 EP disclosed