Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.49 |
| ▸ | CSNK1D | P48730 | 5/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | LCK | P06239 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | STAT1 | P42224 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL211695 | 0.91 | NPC1 (0.55) | CSNK1DHSD17B10LCKNPC1RAB9A | |
| SCHEMBL210507 | 0.88 | CSNK1D (0.47) | DYRK1ACSNK1DLCKNPC1RAB9A | |
| SCHEMBL4342546 | 0.88 | RAB9A (0.58) | DYRK1ACSNK1DNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL211547 | 0.87 | CSNK1D (0.46) | CSNK1DLCKNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL211950 | 0.86 | CSNK1D (0.45) | CSNK1DLCKNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2724495 | 0.85 | CSNK1D (0.47) | DYRK1ACSNK1DHSD17B10LCKNPC1 | |
| SCHEMBL8535100 | 0.83 | SMN1; SMN2 (0.53) | CSNK1DNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL4347836 | 0.82 | CSNK1D (0.51) | CSNK1DNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL8509643 | 0.81 | KMT2A (0.48) | DYRK1ACSNK1DNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL210936 | 0.80 | ALDH1A1 (0.41) | CSNK1DHSD17B10NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120135964-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | QIAN XIANGPING (US) | 2012-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120135964-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | MYLK, MYH2, MYH10 | DYRK1A 4356/4885CSNK1D 754/4885HSD17B10 2636/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.