Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 4/20 | 0.46 |
| ▸ | DKK1 | O94907 | 3/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | MYLK4 | Q86YV6 | 2/20 | 0.38 |
| ▸ | STK17A | Q9UEE5 | 2/20 | 0.38 |
| ▸ | PRKD1 | Q15139 | 2/20 | 0.38 |
| ▸ | PRKD2 | Q9BZL6 | 2/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.37 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.37 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8533322 | 0.99 | KMO (0.46) | KMODKK1CTSSCTSKROCK2 | |
| SCHEMBL8514330 | 0.88 | DKK1 (0.55) | KMODKK1ROCK2 | |
| Hydrochloric Acid SCHEMBL8510232 | 0.87 | DKK1 (0.54) | KMODKK1ROCK2 | |
| SCHEMBL8511790 | 0.83 | ROCK2 (0.41) | KMODKK1ROCK2ADRB1MYLK4 | |
| SCHEMBL8515459 | 0.82 | PRKD1 (0.46) | DKK1ROCK2ADRB1MYLK4STK17A | |
| Hydrochloric Acid SCHEMBL8512525 | 0.82 | ROCK2 (0.41) | KMODKK1ROCK2ADRB1MYLK4 | |
| Hydrochloric Acid SCHEMBL8511580 | 0.82 | ROCK2 (0.41) | KMODKK1ROCK2ADRB1MYLK4 | |
| SCHEMBL8512406 | 0.79 | KMO (0.58) | KMOPDE4D | |
| SCHEMBL8515830 | 0.77 | PRKD1 (0.45) | DKK1ROCK2ADRB1MYLK4STK17A | |
| SCHEMBL8512423 | 0.76 | ADRB1 (0.42) | DKK1ROCK2ADRB1MYLK4STK17A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012069852-A1 | PHARMACEUTICAL COMPOUNDS AS INHIBITORS OF SPHINGOSINE KINASE | ALMAC DISCOVERY LIMITED (GB) | 2012-05-31 | — | — | WO | claimed |
| WO-2012069852-A1 | PHARMACEUTICAL COMPOUNDS AS INHIBITORS OF SPHINGOSINE KINASE | ALMAC DISCOVERY LIMITED (GB) | 2012-05-31 | — | — | WO | disclosed |