Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 5/20 | 0.73 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.73 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.73 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.49 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.49 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | TLR2 | O60603 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9580566 | 0.92 | PRKCA (0.88) | PRKCAPRKCEPRKCQPRKCDALDH1A1 | |
| SCHEMBL2476771 | 0.92 | PRKCA (0.88) | PRKCAPRKCEPRKCQPRKCDALDH1A1 | |
| SCHEMBL12281711 | 0.92 | PRKCA (0.88) | PRKCAPRKCEPRKCQPRKCDALDH1A1 | |
| Succinic Acid SCHEMBL31645179 | 0.89 | PRKCA (0.88) | PRKCAPRKCEPRKCQPRKCDALDH1A1 | |
| Succinic Acid SCHEMBL30448374 | 0.89 | PRKCA (0.88) | PRKCAPRKCEPRKCQPRKCDALDH1A1 | |
| 1,2-Dipalmitin SCHEMBL30513407 | 0.89 | PRKCA (0.88) | PRKCAPRKCEPRKCQPRKCDALDH1A1 | |
| SCHEMBL4254210 | 0.89 | ALDH1A1 (0.68) | PRKCAPRKCEPRKCQPRKCDALDH1A1 | |
| SCHEMBL15359421 | 0.89 | PRKCA (0.76) | PRKCAPRKCEPRKCQPRKCDALDH1A1 | |
| SCHEMBL7113622 | 0.88 | PRKCA (0.86) | PRKCAPRKCEPRKCQPRKCDALDH1A1 | |
| SCHEMBL6461079 | 0.88 | PRKCA (0.86) | PRKCAPRKCEPRKCQPRKCDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210128794-A1 | METHOD COMPRISING CONTACTING TISSUE WITH A CROSS-LINKABLE POLYESTER PREPOLYMER | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2021-05-06 | — | — | US | disclosed |
| US-10864303-B2 | Method comprising contacting tissue with a cross-linkable polyester prepolymer | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2020-12-15 | — | — | US | disclosed |
| US-20190091377-A1 | Biodegradable Elastomers | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2019-03-28 | — | — | US | disclosed |
| US-10179195-B2 | Method comprising contacting tissue with a cross-linkable polyester prepolymer | MASSACHUSETTS INSTITUE OF TECHNOLOGY (US) | 2019-01-15 | — | — | US | disclosed |
| US-20140186312-A1 | Method Comprising Contacting Tissue With a Cross-Linkable Polyester Prepolymer | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2014-07-03 | — | — | US | disclosed |
| US-20120269761-A1 | BIODEGRADABLE ELASTOMERS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2012-10-25 | — | — | US | disclosed |
| US-8143042-B2 | Biodegradable elastomers | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2012-03-27 | — | — | US | disclosed |
| US-20110129436-A1 | POLYGLYCEROL SEBECATE PERITONEAL ADHESION PREVENTION BARRIER | THE GENERAL HOSPITAL CORPORATION (US) | 2011-06-02 | — | — | US | disclosed |
| WO-2009103057-A2 | POLYGLYCEROL SEBECATE PERITONEAL ADHESION PREVENTION BARRIER | THE GENERAL HOSPITAL CORPORATION (US) | 2009-08-20 | — | — | WO | disclosed |
| US-20090047256-A1 | Biodegradable Elastomers | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2009-02-19 | — | — | US | disclosed |
| US-20090011486-A1 | Biodegradable Elastomers | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2009-01-08 | — | — | US | disclosed |
| EP-1973493-A2 | BIODEGRADABLE ELASTOMERS | Massachusetts Institute of Technology (US) | 2008-10-01 | — | — | EP | disclosed |
| WO-2007082304-A2 | BIODEGRADABLE ELASTOMERS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2007-07-19 | — | — | WO | disclosed |
| WO-2007082305-A2 | BIODEGRADABLE ELASTOMERS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2007-07-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140186312-A1 | Method Comprising Contacting Tissue With a Cross-Linkable Polyester Prepolymer | COL14A1, ILK, COL1A1 | PRKCA 3085/4885PRKCE 2568/4885PRKCQ 3727/4885 |
| US-10179195-B2 | Method comprising contacting tissue with a cross-linkable polyester prepolymer | COL14A1, ILK, COL1A1 | PRKCA 3085/4885PRKCE 2568/4885PRKCQ 3727/4885 |
| US-20210128794-A1 | METHOD COMPRISING CONTACTING TISSUE WITH A CROSS-LINKABLE POLYESTER PREPOLYMER | COL14A1, ILK, COL1A1 | PRKCA 3085/4885PRKCE 2568/4885PRKCQ 3727/4885 |
| US-20110129436-A1 | POLYGLYCEROL SEBECATE PERITONEAL ADHESION PREVENTION BARRIER | EPCAM, DSP, CDH1 | PRKCA 2795/4885PRKCE 3250/4885PRKCQ 2504/4885 |
| US-20090047256-A1 | Biodegradable Elastomers | DERA, ALG3, PUF60 | PRKCA 3921/4885PRKCE 3427/4885PRKCQ 4349/4885 |
| US-20190091377-A1 | Biodegradable Elastomers | DERA, ALG3, PUF60 | PRKCA 3921/4885PRKCE 3427/4885PRKCQ 4349/4885 |
| US-10864303-B2 | Method comprising contacting tissue with a cross-linkable polyester prepolymer | COL14A1, ILK, COL1A1 | PRKCA 3085/4885PRKCE 2568/4885PRKCQ 3727/4885 |
| US-20120269761-A1 | BIODEGRADABLE ELASTOMERS | DERA, ALG3, PUF60 | PRKCA 3921/4885PRKCE 3427/4885PRKCQ 4349/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.