SCHEMBL8512573

SCHEMBL8512573

C#CCOc1ccc2ccc(=O)oc2c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 12/20 1.00
CA9 Q16790 12/20 1.00
CA1 P00915 9/20 1.00
CA4 P22748 7/20 1.00
MAOA P21397 8/20 0.72
MAOB P27338 8/20 0.72
MTNR1A P48039 2/20 0.68
CA6 P23280 5/20 0.65
CA7 P43166 5/20 0.65
CA14 Q9ULX7 5/20 0.65
CA5B Q9Y2D0 3/20 0.65
CA5A P35218 3/20 0.65
CYP1A2 P05177 1/20 0.65
KDM4E B2RXH2 2/20 0.62
ALDH1A1 P00352 2/20 0.62
GLA P06280 1/20 0.62
GAA P10253 1/20 0.62
TSHR P16473 1/20 0.62
CA2 P00918 3/20 0.61
CA3 P07451 3/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30127638 1.00 CA12 (1.00) CA12CA9CA1CA4MAOA
SCHEMBL5904507 0.89 CA12 (1.00) CA12CA9CA1CA4MAOA
SCHEMBL8515698 0.84 MAOA (1.00) CA12CA9CA1CA4MAOA
7-(2-Butynyloxy)Coumarin SCHEMBL17682923 0.82 MTNR1A (0.77) CA12CA9CA1CA4MAOA
SCHEMBL12304245 0.82 CA12 (0.81) CA12CA9CA1CA4MAOA
SCHEMBL8512831 0.81 CA12 (1.00) CA12CA9CA1CA4MAOA
7-(2-Pentynyloxy)Coumarin SCHEMBL18292783 0.81 MTNR1A (1.00) CA12CA9CA1CA4MAOA
SCHEMBL17679806 0.80 MTNR1A (0.73) CA12CA9CA1CA4MAOA
SCHEMBL22017341 0.80 CA12 (0.66) CA12CA9CA1CA4MAOA
SCHEMBL11502238 0.80 MAOB (0.66) CA12CA9CA1CA4MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250215028-A1 SYNTHETIC GLYCEROPHOSPHOLIPIDS COMPRISING AT LEAST ONE REACTIVE FUNCTION, PROCESS FOR PREPARING SAME AND USES THEREOF IN DIFFERENT APPLICATIONS UNIVERSITE DE ROUEN-NORMANDIE (FR) 2025-07-03 US disclosed
EP-4499652-A1 SYNTHETIC GLYCEROPHOSPHOLIPIDS COMPRISING AT LEAST ONE REACTIVE FUNCTION, PROCESS FOR PREPARING SAME AND USES THEREOF IN DIFFERENT APPLICATIONS Universite de Rouen Normandie (FR) 2025-02-05 EP disclosed
US-20240213536-A1 Lithium Secondary Battery LG ENERGY SOLUTION, LTD. (KR) 2024-06-27 US disclosed
US-20240213536-A1 Lithium Secondary Battery LG ENERGY SOLUTION, LTD. (KR) 2024-06-27 US disclosed
EP-4329038-A1 NON-AQUEOUS ELECTROLYTE COMPRISING ADDITIVE FOR NON-AQUEOUS ELECTROLYTE, AND LITHIUM SECONDARY BATTERY COMPRISING SAME LG Energy Solution, Ltd. (KR) 2024-02-28 EP disclosed
EP-4329040-A1 NON-AQUEOUS ELECTROLYTE FOR LITHIUM SECONDARY BATTERY AND LITHIUM SECONDARY BATTERY COMPRISING SAME LG Energy Solution, Ltd. (KR) 2024-02-28 EP disclosed
US-11862764-B2 Non-aqueous electrolyte comprising additive for non-aqueous electrolyte, and lithium secondary battery comprising the same LG ENERGY SOLUTION, LTD. 2024-01-02 US disclosed
CN-117337507-A Nonaqueous electrolyte containing additive for nonaqueous electrolyte and lithium secondary battery containing same 株式会社LG新能源 2024-01-02 CN disclosed
US-11862764-B2 Non-aqueous electrolyte comprising additive for non-aqueous electrolyte, and lithium secondary battery comprising the same LG ENERGY SOLUTION, LTD. 2024-01-02 US disclosed
WO-2023219474-A1 NON-AQUEOUS ELECTROLYTE AND LITHIUM SECONDARY BATTERY COMPRISING SAME 주식회사 엘지에너지솔루션 2023-11-16 WO disclosed
WO-2014205414-A1 EXPANDED THERAPEUTIC POTENTIAL IN NITROHETEROARYL ANTIMICROBIALS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2014-12-24 WO disclosed
WO-2014194250-A2 NOVEL NANOCARRIER DELIVERED CANCER CHEMOTHERAPEUTIC AGENTS UNIVERSITY OF CINCINNATI (US) 2014-12-04 WO disclosed
US-20140148400-A1 CARBONIC ANHYDRASE INHIBITORS WITH ANTIMETASTATIC ACTIVITY METASIGNAL THERAPEUTICS INC. (CA) 2014-05-29 US disclosed
US-20140148400-A1 CARBONIC ANHYDRASE INHIBITORS WITH ANTIMETASTATIC ACTIVITY METASIGNAL THERAPEUTICS INC. (CA) 2014-05-29 US disclosed
US-20140148400-A1 CARBONIC ANHYDRASE INHIBITORS WITH ANTIMETASTATIC ACTIVITY METASIGNAL THERAPEUTICS INC. (CA) 2014-05-29 US disclosed
WO-2013028664-A1 PSMA IMAGING AGENTS SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2013-02-28 WO disclosed
CN-102898408-A Benzopyran compounds, preparation method and applications thereof SHANGHAI RUIGUANG BIOCHEMICAL SCIENCE AND TECHNOLOGY DEV CO LTD 2013-01-30 CN disclosed
WO-2012070024-A1 CARBONIC ANHYDRASE INHIBITORS WITH ANTIMETASTATIC ACTIVITY METASIGNAL THERAPEUTICS INC. (CA) 2012-05-31 WO disclosed
WO-2012070024-A1 CARBONIC ANHYDRASE INHIBITORS WITH ANTIMETASTATIC ACTIVITY METASIGNAL THERAPEUTICS INC. (CA) 2012-05-31 WO disclosed
US-4151291-A ANALGESICS UNICLER (FR) 1979-04-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250215028-A1 SYNTHETIC GLYCEROPHOSPHOLIPIDS COMPRISING AT LEAST ONE REACTIVE FUNCTION, PROCESS FOR PREPARING SAME AND USES THEREOF IN DIFFERENT APPLICATIONS PHOSPHO1, SGMS1, SGPL1 CA12 3771/4885CA9 3769/4885CA1 3328/4885
US-20140148400-A1 CARBONIC ANHYDRASE INHIBITORS WITH ANTIMETASTATIC ACTIVITY CA7, CA4, CA2 CA12 10/4885CA9 4/4885CA1 5/4885
US-11862764-B2 Non-aqueous electrolyte comprising additive for non-aqueous electrolyte, and lithium secondary battery comprising the same SLC9A1, SLC26A3, RER1 CA12 923/4885CA9 690/4885CA1 552/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.