SCHEMBL851259

SCHEMBL851259

CC(N)C(=O)CCCCCC(=O)O

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 1/20 0.62
TSHR P16473 5/20 0.55
LMNA P02545 3/20 0.55
NFKB1 P19838 1/20 0.55
PMP22 Q01453 1/20 0.55
ALDH1A1 P00352 4/20 0.52
GPR84 Q9NQS5 7/20 0.50
PPARG P37231 7/20 0.50
PPARD Q03181 7/20 0.50
PPARA Q07869 7/20 0.50
HDAC11 Q96DB2 5/20 0.50
PTPN1 P18031 3/20 0.50
TLR2 O60603 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
MEN1 O00255 2/20 0.50
FABP4 P15090 2/20 0.50
ALOX15 P16050 2/20 0.50
KMT2A Q03164 2/20 0.50
SLC22A6 Q4U2R8 1/20 0.50
SLC22A8 Q8TCC7 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31202391 1.00 LTA4H (0.62) LTA4HTSHRLMNANFKB1PMP22
SCHEMBL21067349 1.00 LTA4H (0.62) LTA4HTSHRLMNANFKB1PMP22
Alanine SCHEMBL15656769 0.86 TSHR (0.60) TSHRLMNANFKB1PMP22ALDH1A1
Alanine SCHEMBL28198684 0.86 TSHR (0.60) TSHRLMNANFKB1PMP22ALDH1A1
Sebacic Acid SCHEMBL15655096 0.86 TSHR (0.60) TSHRLMNANFKB1PMP22ALDH1A1
Azelaic Acid SCHEMBL29465682 0.85 TSHR (0.67) TSHRLMNANFKB1PMP22ALDH1A1
Adipic Acid SCHEMBL15657486 0.83 LMNA (0.58) LTA4HTSHRLMNANFKB1PMP22
SCHEMBL1834739 0.83 TSHR (0.63) TSHRLMNANFKB1PMP22ALDH1A1
Adipic Acid SCHEMBL15657487 0.83 LMNA (0.58) LTA4HTSHRLMNANFKB1PMP22
SCHEMBL1986431 0.83 GABRP (0.54) LTA4HTSHRLMNANFKB1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 316 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4658805-A1 METHODS FOR IDENTIFYING HERBICIDAL COMPOUNDS Syngenta Crop Protection AG (CH) 2025-12-10 EP claimed
US-20240368659-A1 MICROBIAL CELL FACTORIES PRODUCING VITAMIN B COMPOUNDS BIOSYNTIA APS (DK) 2024-11-07 US claimed
CN-118792227-A Method for improving acarbose yield 上海医药工业研究院有限公司 2024-10-18 CN claimed
WO-2024160975-A1 METHODS FOR IDENTIFYING HERBICIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2024-08-08 WO claimed
EP-4370653-A2 MICROBIAL CELL FACTORIES PRODUCING VITAMIN B COMPOUNDS Biosyntia ApS (DK) 2024-05-22 EP claimed
US-11851461-B2 Cell factory having improved iron-sulfur cluster delivery BIOSYNTIA APS (DK) 2023-12-26 US claimed
CN-117143789-A Construction and application of corynebacterium glutamicum for producing ectoin by one-step method 森瑞斯生物科技(深圳)有限公司 2023-12-01 CN claimed
CN-116660543-A Diagnostic and prognostic markers for nonalcoholic fatty liver disease and uses thereof 中国人民解放军陆军军医大学第一附属医院 2023-08-29 CN claimed
CN-115197887-B Full-biological synthesis method for producing pimelic acid by utilizing Kleisen condensation reaction 江南大学 2023-08-25 CN claimed
US-20230192778-A1 CELL FACTORY HAVING IMPROVED IRON-SULFUR CLUSTER DELIVERY BIOSYNTIA APS (DK) 2023-06-22 US claimed
EP-2632903-A2 METALLOENZYME INHIBITOR COMPOUNDS Viamet Pharmaceuticals, Inc. (US) 2013-09-04 EP claimed
WO-2012058529-A2 METALLOENZYME INHIBITOR COMPOUNDS VIAMET PHARMACEUTICALS, INC. (US) 2012-05-03 WO claimed
WO-2012058686-A2 HYBRID POLYKETIDE SYNTHASES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2012-05-03 WO claimed
WO-2011067553-A1 CELLS FOR THE PRODUCTION OF BIOTIN - TAGGED VIRAL VECTORS OR PROTEINS KING'S COLLEGE LONDON (GB) 2011-06-09 WO claimed
US-20100210569-A1 Mitochondria-targeting antioxidant therapeutics STELIOU KOSTA 2010-08-19 US claimed
EP-1577394-B1 DNA fragment containing biotin biosynthesis gene and utilization thereof SUMITOMO CHEMICAL CO (JP) 2009-07-15 EP claimed
EP-0913475-B1 DNA FRAGMENTS CONTAINING BIOTIN BIOSYNTHETASE GENE AND USE OF THE SAME SUMITOMO CHEMICAL CO (JP) 2009-06-03 EP claimed
WO-2009038656-A1 MITOCHONDRIA-TARGETING ANTIOXIDANT THERAPEUTICS STELIOU KOSTA (US) 2009-03-26 WO claimed
US-20040006040-A1 Method for the identification and treatment of pathogenic microorganism infections by inhibiting one or more enzymes in an essential metabolic pathway and compounds and pharmaceutical compositions useful therefor PYRO PHARMACEUTICALS, INC. 2004-01-08 US claimed
EP-0892066-B1 Overcoming DAPA aminotransferase bottlenecks in biotin vitamers HOFFMANN LA ROCHE (CH) 2003-04-09 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040006040-A1 Method for the identification and treatment of pathogenic microorganism infections by inhibiting one or more enzymes in an essential metabolic pathway and compounds and pharmaceutical compositions useful therefor CYP51A1, ME1, BPGM LTA4H 497/4885TSHR 4468/4885LMNA 3872/4885
US-20100210569-A1 Mitochondria-targeting antioxidant therapeutics SLC25A20, TXNRD2, TXN2 LTA4H 1863/4885TSHR 4234/4885LMNA 2330/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.