Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 1/20 | 0.33 |
| ▸ | RARB | P10826 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 3/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | DKK1 | O94907 | 1/20 | 0.30 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8511972 | 0.87 | DKK1 (0.39) | CA9CA2TSHRDKK1FAAH | |
| Hydrochloric Acid SCHEMBL8514429 | 0.86 | DKK1 (0.38) | CA9CA2TSHRDKK1FAAH | |
| SCHEMBL8511490 | 0.82 | DKK1 (0.42) | RARARARBCA9CA2DKK1 | |
| Hydrochloric Acid SCHEMBL8515565 | 0.81 | DKK1 (0.41) | RARARARBCA9CA2DKK1 | |
| SCHEMBL8515254 | 0.77 | RARB (0.51) | RARARARB | |
| SCHEMBL31060783 | 0.77 | RARB (0.51) | RARARARB | |
| SCHEMBL9612771 | 0.76 | RARA (0.41) | RARARARBCA9CA2DKK1 | |
| Hydrochloric Acid SCHEMBL8667697 | 0.75 | RARA (0.41) | RARARARBCA9CA2DKK1 | |
| SCHEMBL8515183 | 0.73 | ACHE (0.48) | FAAH | |
| SCHEMBL8512423 | 0.72 | ADRB1 (0.42) | DKK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012069852-A1 | PHARMACEUTICAL COMPOUNDS AS INHIBITORS OF SPHINGOSINE KINASE | ALMAC DISCOVERY LIMITED (GB) | 2012-05-31 | — | — | WO | claimed |