Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 2/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | AHR | P35869 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5953900 | 0.77 | ADRA2A (0.40) | ADRA2AADRA2BADRA2CAHR | |
| SCHEMBL7571188 | 0.76 | ADRA1D (0.35) | — | |
| SCHEMBL5146376 | 0.75 | GABRA1 (0.42) | ADRA2AADRA2BADRA2C | |
| SCHEMBL5954174 | 0.75 | ADRA2A (0.39) | ADRA2AADRA2BADRA2CAHR | |
| SCHEMBL5954212 | 0.73 | ADRA2A (0.38) | ADRA2AADRA2BADRA2CALDH1A1HPGD | |
| SCHEMBL5954076 | 0.72 | ADRA2A (0.37) | ADRA2AADRA2BADRA2CAHR | |
| SCHEMBL6404951 | 0.72 | THRA (0.36) | — | |
| SCHEMBL5859274 | 0.72 | ACHE (0.45) | — | |
| SCHEMBL8516731 | 0.71 | KDM4E (0.39) | ALDH1A1HPGD | |
| SCHEMBL1453793 | 0.69 | ADRA2A (0.37) | ADRA2AADRA2BADRA2CALDH1A1AHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1572606-A4 | CROSS-COUPLING SYNTHESIS OF ALKYL (DIALKYLPHENYL) INDENES | BOULDER SCIENT CO (US) | 2008-07-09 | — | — | EP | claimed |
| US-7205427-B2 | Cross-coupling synthesis of alkyl (dialkylphenyl) indenes | BOULDER SCIENTIFIC COMPANY (US) | 2007-04-17 | — | — | US | claimed |
| EP-1572606-A2 | CROSS-COUPLING SYNTHESIS OF ALKYL (DIALKYLPHENYL) INDENES | BOULDER SCIENTIFIC COMPANY (US) | 2005-09-14 | — | — | EP | claimed |
| US-20040267072-A1 | Cross-coupling synthesis of alkyl (dialkylphenyl) indenes | ANTARES CAPITAL LP, AS AGENT | 2004-12-30 | — | — | US | claimed |
| WO-2003101601-A2 | CROSS-COUPLING SYNTHESIS OF ALKYL (DIALKYLPHENYL) INDENES | BOULDER SCIENTIFIC COMPANY (US) | 2003-12-11 | — | — | WO | claimed |
| US-20060052620-A1 | Preparation of substituted indenes | BASELL POLYOLEFINE GMBH (DE) | 2006-03-09 | — | — | US | disclosed |
| EP-1492749-A1 | PREPARATION OF SUBSTITUTED INDENES | Basell Polyolefine GmbH (DE) | 2005-01-05 | — | — | EP | disclosed |
| WO-2003084904-A1 | PREPARATION OF SUBSTITUTED INDENES | BASELL POLYOLEFINE GMBH (DE) | 2003-10-16 | — | — | WO | disclosed |
| EP-1123298-A4 | 2-ALKYL-4-(2,6-DIALKYLPHENYL) INDENES | BOULDER SCIENT CO (US) | 2002-08-07 | — | — | EP | disclosed |
| US-6291699-B1 | TO PRODUCE BRIDGED METALLOCENE LIGANDS WHICH CAN BE CONVERTED INTO BRIDGED METALLOCENES USEFUL AS OLFIN POLYMERIZATION CATALYST | BOULDER SCIENTIFIC COMPANY | 2001-09-18 | — | — | US | disclosed |
| EP-1123298-A1 | 2-ALKYL-4-(2,6-DIALKYLPHENYL) INDENES | BOULDER SCIENTIFIC COMPANY (US) | 2001-08-16 | — | — | EP | disclosed |
| WO-2001014388-A1 | 2-ALKYL-4-(2,6-DIALKYLPHENYL) INDENES | BOULDER SCIENTIFIC COMPANY (US) | 2001-03-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040267072-A1 | Cross-coupling synthesis of alkyl (dialkylphenyl) indenes | DDT, DUOX2, DYRK4 | ADRA2A 1763/4885ADRA2B 1560/4885ADRA2C 2140/4885 |
| US-20060052620-A1 | Preparation of substituted indenes | INTS9, CYP1A2, INF2 | ADRA2A 2316/4885ADRA2B 2650/4885ADRA2C 2527/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.