Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.32 |
| ▸ | HPGD | P15428 | 4/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.31 |
| ▸ | ANPEP | P15144 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.31 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.31 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8516731 | 0.75 | KDM4E (0.39) | ALDH1A1HSD17B10CYP2A6TSHRTDP1 | |
| SCHEMBL5954212 | 0.71 | ADRA2A (0.38) | ALDH1A1HPGD | |
| SCHEMBL5859274 | 0.69 | ACHE (0.45) | — | |
| SCHEMBL3056466 | 0.69 | ALDH1A1 (0.41) | ALDH1A1HSD17B10CYP2A6TSHRTDP1 | |
| SCHEMBL7094614 | 0.67 | HSD17B10 (0.38) | ALDH1A1HSD17B10CYP2A6TSHRTDP1 | |
| SCHEMBL11666181 | 0.65 | CYP1A2 (0.43) | ALDH1A1HSD17B10TDP1KDM4EHPGD | |
| SCHEMBL5657362 | 0.65 | WDR5 (0.43) | ALDH1A1HSD17B10TSHRTDP1KDM4E | |
| SCHEMBL30083984 | 0.63 | CYP1A2 (0.52) | ALDH1A1TDP1KDM4EHPGDCYP1A2 | |
| SCHEMBL25106 | 0.63 | CYP1A2 (0.52) | ALDH1A1TDP1KDM4EHPGDCYP1A2 | |
| SCHEMBL16487341 | 0.62 | ALDH1A1 (0.50) | ALDH1A1HSD17B10CYP2A6TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5942636-A | Process of preparing 2-alkyl-2,3-dihydro-1H-benz e!indene-1-one derivatives | AKZO NOBEL N.V. (NL) | 1999-08-24 | — | — | US | claimed |
| EP-0856506-A1 | Process of preparing 2-alkyl-2,3-dihydro-1H-benz(e)indene-1-one derivatives | Akzo Nobel N.V. (NL) | 1998-08-05 | — | — | EP | claimed |
| US-5942636-A | Process of preparing 2-alkyl-2,3-dihydro-1H-benz e!indene-1-one derivatives | AKZO NOBEL N.V. (NL) | 1999-08-24 | — | — | US | disclosed |
| EP-0856506-A1 | Process of preparing 2-alkyl-2,3-dihydro-1H-benz(e)indene-1-one derivatives | Akzo Nobel N.V. (NL) | 1998-08-05 | — | — | EP | disclosed |