Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 4/20 | 0.33 |
| ▸ | THRA | P10827 | 2/20 | 0.33 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9501121 | 0.69 | LMNA (0.36) | LMNAGPR84THRBTHRAPLA2G2A | |
| SCHEMBL7867591 | 0.68 | MEN1 (0.37) | LMNAGPR84CYP1A2MEN1KMT2A | |
| SCHEMBL155738 | 0.67 | ALOX5 (0.45) | — | |
| SCHEMBL11698807 | 0.67 | ALOX5 (0.45) | — | |
| SCHEMBL1268159 | 0.67 | TP53 (0.36) | LMNAGPR84MEN1KMT2ATDP1 | |
| SCHEMBL31592759 | 0.67 | MEN1 (0.40) | LMNAGPR84MEN1KMT2ATDP1 | |
| SCHEMBL30930834 | 0.67 | MEN1 (0.40) | LMNAGPR84MEN1KMT2ATDP1 | |
| SCHEMBL4272289 | 0.65 | CYP19A1 (0.36) | LMNAGPR84PLA2G2A | |
| SCHEMBL9809602 | 0.63 | THRA (0.44) | GPR84THRBTHRAPLA2G2ATP53 | |
| SCHEMBL4009820 | 0.63 | ACHE (0.50) | GPR84PLA2G2ATP53TSHRNR5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5698585-A | FOR SENILE CATARACT CAUSED BY OXIDATION DISORDER; VISION DEFECTS | KIKKOMAN CORPORATION (JP) | 1997-12-16 | — | — | US | claimed |
| EP-0737476-A2 | A pharmaceutical preparation containing a 3-(2H)-furanone derivative for prevention and/or treatment of cataracts | KIKKOMAN CORPORATION (JP) | 1996-10-16 | — | — | EP | claimed |
| JP-11140072-A | — | — | None | — | — | JP | disclosed |
| JP-H11140072-A | 3,4-DIACYLOXYFURAN DERIVATIVE OR ITS SALT AND ITS PRODUCTION | KIKKOMAN CORP | 1999-05-25 | — | — | JP | disclosed |
| US-5698585-A | FOR SENILE CATARACT CAUSED BY OXIDATION DISORDER; VISION DEFECTS | KIKKOMAN CORPORATION (JP) | 1997-12-16 | — | — | US | disclosed |
| EP-0737476-A2 | A pharmaceutical preparation containing a 3-(2H)-furanone derivative for prevention and/or treatment of cataracts | KIKKOMAN CORPORATION (JP) | 1996-10-16 | — | — | EP | disclosed |