SCHEMBL851743

SCHEMBL851743

CCCCCCCCCCCCSC(=S)SC(C)(C#N)CCC(=O)O

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 7/20 0.37
PPARG P37231 7/20 0.37
PPARD Q03181 7/20 0.37
PPARA Q07869 7/20 0.37
HDAC11 Q96DB2 5/20 0.37
TSHR P16473 4/20 0.37
PTPN1 P18031 3/20 0.37
ALDH1A1 P00352 2/20 0.37
TLR2 O60603 2/20 0.37
TDP1 Q9NUW8 2/20 0.37
FABP4 P15090 2/20 0.37
HSD17B10 Q99714 2/20 0.37
KMT2A Q03164 2/20 0.37
SLC22A6 Q4U2R8 1/20 0.37
SLC22A8 Q8TCC7 1/20 0.37
MEN1 O00255 1/20 0.37
ESR1 P03372 1/20 0.37
ALOX15 P16050 1/20 0.37
PDE4A P27815 1/20 0.37
PDE3A Q14432 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19269475 1.00 GPR84 (0.37) GPR84PPARGPPARDPPARAHDAC11
SCHEMBL14486506 1.00 GPR84 (0.37) GPR84PPARGPPARDPPARAHDAC11
SCHEMBL31314992 1.00 GPR84 (0.37) GPR84PPARGPPARDPPARAHDAC11
SCHEMBL23398348 1.00 GPR84 (0.37) GPR84PPARGPPARDPPARAHDAC11
SCHEMBL31314993 1.00 GPR84 (0.37) GPR84PPARGPPARDPPARAHDAC11
SCHEMBL23361291 1.00 GPR84 (0.37) GPR84PPARGPPARDPPARAHDAC11
SCHEMBL20141938 1.00 GPR84 (0.37) GPR84PPARGPPARDPPARAHDAC11
SCHEMBL31379944 0.96 HSD17B10 (0.39) GPR84PPARGPPARDPPARAHDAC11
Methoxymethane SCHEMBL29793921 0.96 GPR84 (0.34) GPR84PPARGPPARDPPARAHDAC11
SCHEMBL2231683 0.95 AKR1B1 (0.33) GPR84PPARGPPARDPPARAHDAC11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1339 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4001345-B1 DEGRADABLE HYPERBRANCHED RESIN, PREPARATION METHOD THEREFOR, AND USE THEREOF UNIV SOUTH CHINA TECH (CN) 2026-04-01 EP claimed
US-12539650-B2 Method for making embedded hydrogel contact lenses ALCON INC. (CH) 2026-02-03 US claimed
US-20260014186-A1 POLYMER NANOPARTICLE AND DNA NANOSTRUCTURE COMPOSITIONS AND METHODS FOR NON-VIRAL DELIVERY BATTELLE MEMORIAL INSTITUTE (US) 2026-01-15 US claimed
WO-2025244983-A1 SELF-HEALING COMPOSITION OF MATTER AND METHODS OF PREPARATION AND USE THEREOF THE PENN STATE RESEARCH FOUNDATION (US) 2025-11-27 WO claimed
CN-119812455-A Brush polymer electrolyte, controllable preparation method and application 浙江新安化工集团股份有限公司 2025-04-11 CN claimed
EP-4514595-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES Alcon Inc. (CH) 2025-03-05 EP claimed
CN-119425396-A Electropositive heterogeneous membrane and preparation and application thereof 中国科学院大连化学物理研究所 2025-02-14 CN claimed
CN-119405840-A Oral tryptophan metabolite micelle for treating ulcerative colitis and preparation method and application thereof 山东大学 2025-02-11 CN claimed
EP-4490209-A1 RANDOM HETEROPOLYMER EXCIPIENTS FOR HIGH PROTEIN CONCENTRATION FORMULATIONS Genentech Inc. (US) 2025-01-15 EP claimed
US-20240426835-A1 Random Heteropolymer Excipients For High Protein Concentration Formulations GENENTECH, INC. (US) 2024-12-26 US claimed
EP-2634198-A1 Copolymers containing phosphorylcholine groups and methods of preparing and using the same Suntech Co., Ltd. (KR) 2013-09-04 EP claimed
US-20130165588-A1 METHOD OF MAKING A GRAFT COPOLYMER MRUK RALF (LU) 2013-06-27 US claimed
US-8383744-B2 Actinically-crosslinkable siloxane-containing copolymers NOVARTIS AG (CH) 2013-02-26 US claimed
EP-2432808-A1 ACTINICALLY-CROSSLINKABLE SILOXANE-CONTAINING COPOLYMERS Novartis AG (CH) 2012-03-28 EP claimed
WO-2010133680-A1 ACTINICALLY-CROSSLINKABLE SILOXANE-CONTAINING COPOLYMERS NOVARTIS AG (CH) 2010-11-25 WO claimed
US-20100296049-A1 ACTINICALLY-CROSSLINKABLE SILOXANE-CONTAINING COPOLYMERS ALCON INC. (CH) 2010-11-25 US claimed
US-7408013-B2 Low-polydispersity photoimageable polymers and photoresists and processes for microlithography COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANIZATION (AT) 2008-08-05 US claimed
EP-1673662-A1 LOW-POLYDISPERSITY PHOTOIMAGEABLE POLYMERS AND PHOTORESISTS AND PROCESSES FOR MICROLITHOGRAPHY E.I. DUPONT DE NEMOURS AND COMPANY (US) 2006-06-28 EP claimed
US-20050112495-A1 Low-polydispersity photoimageable polymers and photoresists and processes for microlithography COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2005-05-26 US claimed
WO-2005031462-A1 LOW-POLYDISPERSITY PHOTOIMAGEABLE POLYMERS AND PHOTORESISTS AND PROCESSES FOR MICROLITHOGRAPHY E.I. DUPONT DE NEMOURS AND COMPANY (US) 2005-04-07 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12539650-B2 Method for making embedded hydrogel contact lenses INF2, CRYZ, CRYAA GPR84 4220/4885PPARG 4217/4885PPARD 3464/4885
US-20100296049-A1 ACTINICALLY-CROSSLINKABLE SILOXANE-CONTAINING COPOLYMERS VCL, MACF1, CFL1 GPR84 2856/4885PPARG 1433/4885PPARD 1904/4885
US-20260014186-A1 POLYMER NANOPARTICLE AND DNA NANOSTRUCTURE COMPOSITIONS AND METHODS FOR NON-VIRAL DELIVERY POLRMT, FUS, POLM GPR84 4598/4885PPARG 4731/4885PPARD 4037/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.