Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 3/20 | 0.30 |
| ▸ | CTSK | P43235 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7719979 | 0.78 | TDP1 (0.48) | MEN1KMT2A | |
| SCHEMBL28165431 | 0.72 | ITGB3 (0.34) | DGAT1 | |
| SCHEMBL29454707 | 0.68 | DGAT1 (0.34) | MEN1KMT2ADGAT1 | |
| SCHEMBL8611222 | 0.68 | MEN1 (0.39) | MEN1KMT2ADGAT1CTSSCTSK | |
| SCHEMBL16411264 | 0.67 | DGAT1 (0.33) | DGAT1 | |
| SCHEMBL8797158 | 0.67 | DGAT1 (0.38) | DGAT1 | |
| SCHEMBL3294151 | 0.67 | DGAT1 (0.38) | DGAT1 | |
| SCHEMBL27831974 | 0.66 | MEN1 (0.37) | MEN1KMT2ADGAT1CTSSCTSK | |
| SCHEMBL13305942 | 0.65 | MEN1 (0.38) | MEN1KMT2ADGAT1 | |
| SCHEMBL1304101 | 0.65 | TDP1 (0.53) | MEN1KMT2ACTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6001824-A | Butyryl-tyrosinyl spermine, analogs thereof and methods of preparing and using same | THE TRUSTEES OF COLUMBIA UNIVERSITY (US) | 1999-12-14 | — | — | US | disclosed |
| WO-1996022962-A1 | BUTYRYL-TYROSINYL SPERMINE, ANALOGS THEREOF AND METHODS OF PREPARING AND USING SAME | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 1996-08-01 | — | — | WO | disclosed |