Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 11/20 | 0.41 |
| ▸ | CA2 | P00918 | 11/20 | 0.41 |
| ▸ | CA12 | O43570 | 7/20 | 0.41 |
| ▸ | CA9 | Q16790 | 7/20 | 0.41 |
| ▸ | STK17B | O94768 | 1/20 | 0.38 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.34 |
| ▸ | FPR3 | P25089 | 1/20 | 0.34 |
| ▸ | FPR2 | P25090 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14485 | 0.80 | TDP1 (0.65) | TDP1MAOAMAOBMEN1GAA | |
| SCHEMBL181700 | 0.78 | TDP1 (0.68) | TDP1MAOAMAOBMEN1GAA | |
| Ammonia Solution, Strong SCHEMBL18526745 | 0.78 | TDP1 (0.62) | TDP1MAOAMAOBMEN1GAA | |
| Hydrochloric Acid SCHEMBL5973450 | 0.78 | TDP1 (0.62) | TDP1MAOAMAOBMEN1GAA | |
| SCHEMBL30918591 | 0.78 | TDP1 (0.56) | TDP1MAOAMAOBMEN1GAA | |
| SCHEMBL8517870 | 0.78 | MEN1 (0.33) | MEN1KMT2A | |
| SCHEMBL12502050 | 0.77 | MAOA (0.62) | TDP1MAOAMAOBMEN1GAA | |
| SCHEMBL29778251 | 0.77 | MAOA (0.62) | TDP1MAOAMAOBMEN1GAA | |
| SCHEMBL220281 | 0.77 | TDP1 (0.71) | TDP1MAOAMAOBMEN1GAA | |
| SCHEMBL989107 | 0.77 | TDP1 (0.71) | TDP1MAOAMAOBMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1187807-A1 | BIPOLAR LIPIDS AND THEIR USE FOR THE DELIVERY OF BIOACTIVE SUBSTANCES | Celltech R&D Limited (GB) | 2002-03-20 | — | — | EP | disclosed |
| WO-2000064858-A1 | BIPOLAR LIPIDS AND THEIR USE FOR THE DELIVERY OF BIOACTIVE SUBSTANCES | CELLTECH R&D LIMITED (GB) | 2000-11-02 | — | — | WO | disclosed |