Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8518661 | 0.88 | POLB (0.38) | ALDH1A1POLBMMP13LMNASMN1; SMN2 | |
| SCHEMBL8518959 | 0.86 | NAMPT (0.46) | TSHRALDH1A1KCNJ1POLBLMNA | |
| SCHEMBL8519895 | 0.82 | ABCB11 (0.51) | TSHRALDH1A1POLBLMNASMN1; SMN2 | |
| SCHEMBL8518478 | 0.82 | MEN1 (0.43) | TSHRALDH1A1POLBNAMPTHTT | |
| Hydrochloric Acid SCHEMBL8518624 | 0.82 | VNN1 (0.43) | TSHRPOLBNAMPTHPGDHTT | |
| Hydrochloric Acid SCHEMBL8519131 | 0.81 | ABCB11 (0.50) | TSHRALDH1A1POLBLMNASMN1; SMN2 | |
| SCHEMBL8519457 | 0.80 | GAA (0.48) | TSHRALDH1A1MMP13SMN1; SMN2NAMPT | |
| SCHEMBL8519780 | 0.80 | LMNA (0.41) | TSHRALDH1A1LMNASMN1; SMN2NAMPT | |
| SCHEMBL8518393 | 0.77 | PTGS2 (0.47) | TSHRALDH1A1POLBMMP13LMNA | |
| SCHEMBL8519831 | 0.76 | KCNJ1 (0.33) | TSHRALDH1A1KCNJ1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5952368-A | AN INHIBITORS OF PROSTAGLANDIN G/H SYNTHASE, ANTIINFLAMMATORY AND ANALGESIC AGENTS | SYNTEX (U.S.A.) INC. (US) | 1999-09-14 | — | — | US | disclosed |