Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8518478 | 0.89 | MEN1 (0.43) | GAAALDH1A1NAMPTTSHRHTT | |
| SCHEMBL8519895 | 0.89 | ABCB11 (0.51) | SMN1; SMN2ALDH1A1NAMPTTSHRHTT | |
| Hydrochloric Acid SCHEMBL8518624 | 0.89 | VNN1 (0.43) | NAMPTTSHRHTT | |
| SCHEMBL8519156 | 0.89 | OPRK1 (0.46) | SMN1; SMN2ALDH1A1MMP1MMP13KCNA5 | |
| Hydrochloric Acid SCHEMBL8519131 | 0.88 | ABCB11 (0.50) | SMN1; SMN2ALDH1A1NAMPTTSHRHTT | |
| SCHEMBL8519780 | 0.85 | LMNA (0.41) | SMN1; SMN2ALDH1A1NAMPTTSHRHTT | |
| SCHEMBL8518342 | 0.80 | TSHR (0.43) | SMN1; SMN2ALDH1A1MMP13NAMPTTSHR | |
| SCHEMBL8518402 | 0.79 | ABCB11 (0.47) | SMN1; SMN2ALDH1A1MMP1MMP9MMP13 | |
| SCHEMBL8518393 | 0.78 | PTGS2 (0.47) | GAASMN1; SMN2ALDH1A1MMP1MMP9 | |
| SCHEMBL8519370 | 0.77 | ABCB11 (0.46) | SMN1; SMN2ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5952368-A | AN INHIBITORS OF PROSTAGLANDIN G/H SYNTHASE, ANTIINFLAMMATORY AND ANALGESIC AGENTS | SYNTEX (U.S.A.) INC. (US) | 1999-09-14 | — | — | US | disclosed |