Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HPGDS | O60760 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8518402 | 0.85 | ABCB11 (0.47) | SMN1; SMN2HPGDKDM4EALDH1A1POLB | |
| SCHEMBL8519559 | 0.83 | ABCB11 (0.38) | SMN1; SMN2HPGDALDH1A1POLBGAA | |
| SCHEMBL8518393 | 0.82 | PTGS2 (0.47) | SMN1; SMN2HPGDKDM4EALDH1A1POLB | |
| SCHEMBL8519019 | 0.80 | SMN1; SMN2 (0.41) | KMT2ASMN1; SMN2HPGDMEN1KDM4E | |
| SCHEMBL8518493 | 0.80 | ABCB11 (0.60) | KMT2ASMN1; SMN2HPGDMEN1ALDH1A1 | |
| SCHEMBL8519370 | 0.80 | ABCB11 (0.46) | KMT2ASMN1; SMN2HPGDKDM4EALDH1A1 | |
| SCHEMBL8519798 | 0.80 | ABCB11 (0.43) | SMN1; SMN2HPGDALDH1A1L3MBTL1LMNA | |
| SCHEMBL8519156 | 0.78 | OPRK1 (0.46) | KMT2ASMN1; SMN2MEN1ALDH1A1LMNA | |
| SCHEMBL7678426 | 0.77 | PTGS2 (0.57) | KMT2ASMN1; SMN2HPGDMEN1ALOX15 | |
| SCHEMBL8520245 | 0.75 | ALDH1A1 (0.38) | KMT2ASMN1; SMN2HPGDMEN1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5952368-A | AN INHIBITORS OF PROSTAGLANDIN G/H SYNTHASE, ANTIINFLAMMATORY AND ANALGESIC AGENTS | SYNTEX (U.S.A.) INC. (US) | 1999-09-14 | — | — | US | disclosed |