Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | ACLY | P53396 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GALR3 | O60755 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8518402 | 0.90 | ABCB11 (0.47) | ABCB11PTGS2ALDH1A1LMNACYP1A2 | |
| SCHEMBL8519370 | 0.89 | ABCB11 (0.46) | ABCB11PTGS2ALDH1A1LMNACYP1A2 | |
| SCHEMBL8518393 | 0.89 | PTGS2 (0.47) | ABCB11PTGS2L3MBTL1ALDH1A1LMNA | |
| SCHEMBL8518493 | 0.87 | ABCB11 (0.60) | ABCB11PTGS2L3MBTL1ALDH1A1LMNA | |
| SCHEMBL8519156 | 0.85 | OPRK1 (0.46) | ABCB11PTGS2ALDH1A1LMNACYP1A2 | |
| SCHEMBL8519559 | 0.81 | ABCB11 (0.38) | ABCB11PTGS2ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL8519019 | 0.81 | SMN1; SMN2 (0.41) | ABCB11PTGS2ACLYL3MBTL1ALDH1A1 | |
| SCHEMBL8520241 | 0.80 | KMT2A (0.38) | ABCB11PTGS2L3MBTL1ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL8518624 | 0.79 | VNN1 (0.43) | ABCB11PTGS2CYP1A2TSHRHPGD | |
| SCHEMBL8519533 | 0.79 | ABCB11 (0.57) | ABCB11PTGS2L3MBTL1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5952368-A | AN INHIBITORS OF PROSTAGLANDIN G/H SYNTHASE, ANTIINFLAMMATORY AND ANALGESIC AGENTS | SYNTEX (U.S.A.) INC. (US) | 1999-09-14 | — | — | US | disclosed |