SCHEMBL8518848

SCHEMBL8518848

C=C(C)c1ccc(OC#N)c(C)c1

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PDE4A P27815 3/20 0.36
PDE4B Q07343 3/20 0.36
PDE4C Q08493 3/20 0.36
PDE4D Q08499 3/20 0.36
ALOX15 P16050 1/20 0.34
TAS1R3 Q7RTX0 2/20 0.31
TAS1R1 Q7RTX1 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10414443 0.80 ALOX15 (0.39) PDE4APDE4BPDE4CPDE4DALOX15
SCHEMBL23732010 0.78 ALOX15 (0.53) PDE4APDE4BPDE4CPDE4DALOX15
SCHEMBL7644124 0.75 TAS1R3 (0.37) PDE4APDE4BPDE4CPDE4DALOX15
SCHEMBL7639879 0.74 ALOX15 (0.35) PDE4APDE4BPDE4CPDE4DALOX15
SCHEMBL7641670 0.74 TSHR (0.51)
SCHEMBL8985167 0.74 GAA (0.44) ALOX15
SCHEMBL11033634 0.74 ALDH1A1 (0.38)
SCHEMBL29489134 0.74 GAA (0.44) ALOX15
SCHEMBL18724341 0.73 S1PR3 (0.44)
SCHEMBL7733741 0.72 MAPT (0.37) PDE4APDE4BPDE4CPDE4D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4600760-A Thermosettable resin composition containing alkenyl phenyl cyanate THE DOW CHEMICAL COMPANY (US) 1986-07-15 US claimed
US-4581425-A WITH AROMATIC POLYCYANATE, POLYMALEIMIDE, AND UNSATURATED AROMATIC MONOMER THE DOW CHEMICAL COMPANY (US) 1986-04-08 US claimed
US-4558115-A Thermosettable resin compositions containing a polyepoxide and an alkenyl phenyl cyanate THE DOW CHEMICAL COMPANY (US) 1985-12-10 US claimed
EP-0409069-B1 Mesogenic polycyanates and polycyanamides and thermosets thereof DOW CHEMICAL CO (US) 1999-06-02 EP disclosed
EP-0409070-B1 Mesogenic cyanite functional maleimides and thermosets thereof DOW CHEMICAL CO (US) 1999-03-03 EP disclosed
US-5612479-A Polyphenols containing mesogenic moieties as lateral substituents THE DOW CHEMICAL COMPANY (US) 1997-03-18 US disclosed
US-5470946-A Products resulting from polymerizing or curing polycyanates containing mesogenic moieties as lateral substituents THE DOW CHEMICAL COMPANY (US) 1995-11-28 US disclosed
US-5442039-A Rod-like mesogenic structures incorporated into polytriazine products; improved tensile strength, flexural strength THE DOW CHEMICAL COMPANY (US) 1995-08-15 US disclosed
US-5428125-A Liquid crystalline THE DOW CHEMICAL COMPANY (US) 1995-06-27 US disclosed
US-5399673-A Polymerizable monomers THE DOW CHEMICAL COMPANY (US) 1995-03-21 US disclosed
US-5248757-A Curable composition THE DOW CHEMICAL COMPANY (US) 1993-09-28 US disclosed
US-4945138-A Styrylaza vinyl esters THE DOW CHEMICAL COMPANY (US) 1990-07-31 US disclosed
US-4883844-A FROM AROMATIC ALDEHYDE AND SUBSTITUTED PYRIDINE THE DOW CHEMICAL COMPANY (US) 1989-11-28 US disclosed
US-4851483-A FROM EPOXIDIZED HYDROXYSTYRYLAZA COMPOUNDS DERIVED FROM AROMATIC HYDROXYALDEHYDES AND METHYLATED PYRIDINES OR PYRAZINES THE DOW CHEMICAL COMPANY (US) 1989-07-25 US disclosed
US-4600760-A Thermosettable resin composition containing alkenyl phenyl cyanate THE DOW CHEMICAL COMPANY (US) 1986-07-15 US disclosed
US-4581425-A WITH AROMATIC POLYCYANATE, POLYMALEIMIDE, AND UNSATURATED AROMATIC MONOMER THE DOW CHEMICAL COMPANY (US) 1986-04-08 US disclosed
US-4578439-A Styryl pyridine cyanates, styryl pyrazine cyanates and polymers thereof THE DOW CHEMICAL COMPANY (US) 1986-03-25 US disclosed
US-4559399-A CURABLE MIXTURE OF ALKENYLPHENYL CYANATE, AROMATIC POLYCYANATE ANDUNSATURATED COMPOUND; HIGH STRENGH POLYTRIAZINES THE DOW CHEMICAL COMPANY (US) 1985-12-17 US disclosed
US-4558115-A Thermosettable resin compositions containing a polyepoxide and an alkenyl phenyl cyanate THE DOW CHEMICAL COMPANY (US) 1985-12-10 US disclosed
US-4546131-A COPOLYMERS OF ETHYLENICALLY UNSATURATED COMPOUNDS AND ALKENYLPHENYL CYANATE THE DOW CHEMICAL COMPANY (US) 1985-10-08 US disclosed