Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | USP5 | P45974 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8411315 | 0.71 | MEN1 (0.56) | RAB9ANPC1KMT2AMEN1KDM4E | |
| SCHEMBL909202 | 0.69 | NPC1 (0.48) | RAB9ANPC1KMT2AMEN1KDM4E | |
| SCHEMBL8520030 | 0.69 | MEN1 (0.49) | RAB9ANPC1KMT2AMEN1KDM4E | |
| SCHEMBL11114878 | 0.64 | MEN1 (0.42) | RAB9ANPC1KMT2AMEN1CYP3A4 | |
| SCHEMBL5909835 | 0.63 | CTSG (0.49) | KMT2AMEN1KDM4ESMN1; SMN2CYP2C19 | |
| SCHEMBL7287735 | 0.62 | SMN1; SMN2 (0.39) | RAB9AKMT2AMEN1SMN1; SMN2LMNA | |
| SCHEMBL9006342 | 0.62 | RAD52 (0.52) | KMT2AMEN1KDM4ELMNACYP2C19 | |
| SCHEMBL921684 | 0.62 | NPC1 (0.51) | RAB9ANPC1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL1111106 | 0.61 | MEN1 (0.50) | RAB9ANPC1KMT2AMEN1KDM4E | |
| SCHEMBL7062412 | 0.60 | DPP4 (0.36) | KMT2AMEN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0932598-A1 | ASPARTATE ESTER INHIBITORS OF INTERLEUKIN-1$g(b) CONVERTING ENZYME | WARNER-LAMBERT COMPANY (US) | 1999-08-04 | — | — | EP | disclosed |
| WO-1998016502-A1 | ASPARTATE ESTER INHIBITORS OF INTERLEUKIN-1β CONVERTING ENZYME | WARNER-LAMBERT COMPANY (US) | 1998-04-23 | — | — | WO | disclosed |