Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | MGLL | Q99685 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | UGCG | Q16739 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | FAAH | O00519 | 2/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23676376 | 0.79 | MGLL (0.60) | MGLLTDP1ALDH1A1FAAHHSP90AA1 | |
| SCHEMBL4796187 | 0.79 | FAAH (0.50) | MEN1KMT2ANPC1RAB9AMGLL | |
| SCHEMBL6392634 | 0.79 | MGLL (0.50) | MEN1KMT2ANPC1RAB9AMGLL | |
| SCHEMBL22862147 | 0.78 | MGLL (0.47) | MEN1KMT2AMGLLTDP1ALDH1A1 | |
| SCHEMBL14013357 | 0.78 | RAB9A (0.50) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL19901335 | 0.76 | NPC1 (0.44) | MEN1KMT2ANPC1RAB9AMGLL | |
| SCHEMBL3823955 | 0.75 | NOX4 (0.39) | GRM2 | |
| SCHEMBL21702652 | 0.75 | VHL (0.40) | RAB9AMGLLHPGDFAAH | |
| SCHEMBL23627343 | 0.75 | ALDH1A1 (0.39) | MGLLMAPTTDP1ALDH1A1FAAH | |
| SCHEMBL1364061 | 0.75 | MGLL (0.55) | MEN1KMT2ANPC1RAB9AMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5169893-A | Solvent system from which articles can be formed | THE DOW CHEMICAL COMPANY (US) | 1992-12-08 | — | — | US | claimed |
| US-12590078-B2 | — | — | 2026-03-31 | — | — | US | disclosed |
| WO-2023163086-A1 | RESIN COMPOSITION, PREPREG, LAMINATED BOARD, RESIN FILM, PRINTED WIRING BOARD, AND SEMICONDUCTOR PACKAGE | 株式会社レゾナック | 2023-08-31 | — | — | WO | disclosed |
| US-20230180758-A1 | SUBSTITUTED PYRROLINE-2-ONES AND THEIR USE AS HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2023-06-15 | — | — | US | disclosed |
| WO-2023074646-A1 | RESIN-COATED METAL FOIL, PRINTED WIRING BOARD AND MANUFACTURING METHOD THEREOF, AND SEMICONDUCTOR PACKAGE | 株式会社レゾナック | 2023-05-04 | — | — | WO | disclosed |
| EP-4157851-A1 | SUBSTITUTED PYRROLINE-2-ONES AND THEIR USE AS HERBICIDES | Bayer Aktiengesellschaft (DE) | 2023-04-05 | — | — | EP | disclosed |
| CN-115702157-A | Substituted pyrrolin-2-ones and their use as herbicides | 拜耳公司 | 2023-02-14 | — | — | CN | disclosed |
| US-20220213059-A1 | INHIBITING USP19 | Valo Health, LLC | 2022-07-07 | — | — | US | disclosed |
| WO-2021239673-A1 | SUBSTITUTED PYRROLINE-2-ONES AND THEIR USE AS HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2021-12-02 | — | — | WO | disclosed |
| US-11136454-B2 | Thermosetting resin composition and its production method, prepreg, laminate, and printed wiring board | SHOWA DENKO MATERIALS CO., LTD. (JP) | 2021-10-05 | — | — | US | disclosed |
| US-9745332-B2 | Catalysts and processes for the hydrogenation of amides | THE GOVERNORS OF THE UNIVERITY OF ALBERTA (CA) | 2017-08-29 | — | — | US | disclosed |
| EP-2945950-B1 | ISOMANNIDE DERIVATIVES AS INHIBITORS OF SOLUBLE EPOXIDE HYDROLASE | SANOFI SA (FR) | 2017-03-01 | — | — | EP | disclosed |
| US-20140163225-A1 | CATALYSTS AND PROCESSES FOR THE HYDROGENATION OF AMIDES | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2014-06-12 | — | — | US | disclosed |
| EP-2734299-A1 | CATALYSTS AND PROCESSES FOR THE HYDROGENATION OF AMIDES | The Governors of the University of Alberta (CA) | 2014-05-28 | — | — | EP | disclosed |
| WO-2013010275-A1 | CATALYSTS AND PROCESSES FOR THE HYDROGENATION OF AMIDES | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2013-01-24 | — | — | WO | disclosed |
| EP-2278968-A2 | 1,5-DIPHENYL-PYRROLIDIN-2-ONE COMPOUNDS AS CB-1 LIGANDS | ELI LILLY AND COMPANY (US) | 2011-02-02 | — | — | EP | disclosed |
| WO-2009131814-A2 | 1,5-DIPHENYL-PYRROLIDIN-2-ONE COMPOUNDS AS CB-1 LIGANDS | ELI LILLY AND COMPANY (US) | 2009-10-29 | — | — | WO | disclosed |
| US-6500821-B1 | TREAT VARIOUS FORMS OF EPILEPSIES AND OF STATES OF ANXIETY AND TENSION. | ARZNEIMITTELWERK DRESDEN GMBH (DE) | 2002-12-31 | — | — | US | disclosed |
| EP-1212297-A1 | 4-AMINO-1-ARYL-1,5-DIHYDRO-PYRROLE-2-ONE WITH ANTI-CONVULSIVE AND ANXIOLYTIC PROPERTIES AND A METHOD FOR PRODUCING THE SAME | ARZNEIMITTELWERK DRESDEN GMBH (DE) | 2002-06-12 | — | — | EP | disclosed |
| WO-2001019793-A1 | 4-AMINO-1-ARYL-1,5-DIHYDRO-PYRROLE-2-ONE WITH ANTI-CONVULSIVE AND ANXIOLYTIC PROPERTIES AND A METHOD FOR PRODUCING THE SAME | ARZNEIMITTELWERK DRESDEN GMBH (DE) | 2001-03-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220213059-A1 | INHIBITING USP19 | USP19, UBQLN2, UBQLN1 | MEN1 3843/4885KMT2A 2533/4885NPC1 3955/4885 |
| US-12590078-B2 | — | ADRM1, USP19, USP1 | MEN1 3638/4885KMT2A 2342/4885NPC1 3279/4885 |
| US-20140163225-A1 | CATALYSTS AND PROCESSES FOR THE HYDROGENATION OF AMIDES | KAT2A, NAAA, KAT8 | MEN1 1341/4885KMT2A 206/4885NPC1 3021/4885 |
| US-20230180758-A1 | SUBSTITUTED PYRROLINE-2-ONES AND THEIR USE AS HERBICIDES | DDT, HPD, ALDH18A1 | MEN1 4567/4885KMT2A 1688/4885NPC1 4849/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.