Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 7/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 7/20 | 0.46 |
| ▸ | PDK3 | Q15120 | 7/20 | 0.46 |
| ▸ | PDK4 | Q16654 | 7/20 | 0.46 |
| ▸ | ACE | P12821 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29746320 | 0.88 | PDK1 (0.48) | PDK1PDK2PDK3PDK4ACE | |
| SCHEMBL8522807 | 0.81 | PDK1 (0.43) | PDK1PDK2PDK3PDK4ACE | |
| SCHEMBL26613362 | 0.79 | RIPK1 (0.45) | PDK1PDK2PDK3PDK4ACE | |
| SCHEMBL29746522 | 0.79 | RIPK1 (0.45) | PDK1PDK2PDK3PDK4ACE | |
| SCHEMBL16036390 | 0.79 | MEN1 (0.43) | PDK1PDK2PDK3PDK4ACE | |
| SCHEMBL8522615 | 0.75 | MTNR1A (0.48) | ACE | |
| SCHEMBL10441501 | 0.72 | ALDH1A1 (0.40) | PDK1PDK2PDK3PDK4TSHR | |
| SCHEMBL23113116 | 0.72 | NOTUM (0.51) | ACE | |
| SCHEMBL8554748 | 0.72 | TSHR (0.42) | TSHRPKMHPGDNPSR1 | |
| SCHEMBL10683163 | 0.72 | CHRNB2 (0.44) | TSHRPKMHPGDNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996024587-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 1996-08-15 | — | — | WO | claimed |
| EP-0907374-A1 | GROWTH HORMONE COMPONENT AND BONE ANTI-RESORPTIVE AGENT IN CYCLIC (COHERENCE) TREATMENT OF OSTEOPOROSIS | NOVO NORDISK A/S (DK) | 1999-04-14 | — | — | EP | disclosed |
| WO-1997046252-A1 | GROWTH HORMONE COMPONENT AND BONE ANTI-RESORPTIVE AGENT IN CYCLIC (COHERENCE) TREATMENT OF OSTEOPOROSIS | NOVO NORDISK A/S (DK) | 1997-12-11 | — | — | WO | disclosed |
| WO-1996024587-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 1996-08-15 | — | — | WO | disclosed |