SCHEMBL8523523

SCHEMBL8523523

C=CC[SiH](c1ccc(C)cc1)c1ccc(C)cc1

nearest known ligand 0.36

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
MMP9 P14780 1/20 0.34
MMP2 P08253 1/20 0.33
C5AR1 P21730 1/20 0.32
TGM2 P21980 1/20 0.31
NPSR1 Q6W5P4 2/20 0.31
IDO1 P14902 1/20 0.31
CYP2A6 P11509 1/20 0.31
KDM4E B2RXH2 1/20 0.30
SMN1; SMN2 Q16637 2/20 0.30
NPC1 O15118 1/20 0.30
RAB9A P51151 1/20 0.30
ALDH1A1 P00352 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL216362 0.76 ALDH1A1 (0.36) ALDH1A1
P-Xylene SCHEMBL459337 0.69 ACHE (0.50) ACHETDP1MMP9C5AR1TGM2
SCHEMBL10318764 0.69 ACHE (0.42) ACHETDP1NPSR1IDO1CYP2A6
SCHEMBL8440584 0.69 ACHE (0.42) ACHETDP1MMP2TGM2NPSR1
P-Xylene SCHEMBL27502894 0.67 TSHR (0.53) ACHETDP1MMP9TGM2NPSR1
SCHEMBL16594002 0.67 ACHE (0.40) ACHETDP1MMP2TGM2NPSR1
P-Xylene SCHEMBL28049921 0.65 ACHE (0.61) ACHETDP1TGM2NPSR1IDO1
SCHEMBL8967619 0.64 ACHE (0.50) ACHETDP1IDO1CYP2A6SMN1; SMN2
SCHEMBL28998330 0.64 LMNA (0.43) ACHETDP1NPSR1KDM4ESMN1; SMN2
P-Xylene SCHEMBL11137342 0.64 NPSR1 (0.44) ACHETDP1TGM2NPSR1CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1182179-C Di-p-tolyl-dialkyl silane derivative and its produced photoluminescence polymer and method of preparing these compounds 三星电管株式会社 2004-12-29 CN disclosed
CN-1098855-C Di-p-tolylalkylsilane derivatives and photoluminescent polymers derived therefrom and process for preparing these compounds SAMSUNG DISPLAY DEVICES CO LTD (KR) 2003-01-15 CN disclosed
CN-1379054-A Di-p-tolyl-dialkyl silane derivative and its produced photoluminescence polymer and method of preparing these compounds SAMSUNG DISPLAY DEVICES CO LTD (KR) 2002-11-13 CN disclosed
US-5990335-A Di-p-tolydialkylsilane derivative and photoluminescene polymer formed therefrom and methods for preparing these compounds SAMSUNG DISPLAY DEVICES CO., LTD. (KR) 1999-11-23 US disclosed
CN-1196355-A Di-p-tolylalkylsilane derivatives and photoluminescent polymers derived therefrom and process for preparing these compounds SAMSUNG DISPLAY DEVICES CO LTD (KR) 1998-10-21 CN disclosed