Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 14/20 | 0.32 |
| ▸ | RXRG | P48443 | 8/20 | 0.32 |
| ▸ | RXRB | P28702 | 6/20 | 0.32 |
| ▸ | RARB | P10826 | 4/20 | 0.32 |
| ▸ | RARG | P13631 | 4/20 | 0.32 |
| ▸ | RARA | P10276 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8309204 | 0.83 | RXRA (0.48) | RXRARXRGRXRBRARBRARG | |
| SCHEMBL8309207 | 0.83 | RXRA (0.48) | RXRARXRGRXRBRARBRARG | |
| SCHEMBL8323697 | 0.74 | RXRA (0.32) | RXRARXRGRXRBRARBRARG | |
| SCHEMBL8320884 | 0.73 | RXRA (0.32) | RXRARXRGRXRBRARBRARG | |
| SCHEMBL8417708 | 0.70 | RXRA (0.52) | RXRARXRGRXRBRARBRARG | |
| SCHEMBL8009347 | 0.68 | RXRA (0.41) | RXRARXRGRXRBRARBRARG | |
| SCHEMBL8015602 | 0.67 | RXRA (0.69) | RXRARXRGRXRBRARBRARG | |
| SCHEMBL8011713 | 0.66 | RXRA (0.41) | RXRARXRGRXRBRARBRARG | |
| SCHEMBL8005485 | 0.65 | RXRA (0.43) | RXRARXRGRXRBRARBRARG | |
| SCHEMBL6037055 | 0.64 | RXRA (0.52) | RXRARXRGRXRBRARBRARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0800504-B1 | TRICYCLIC RETINOIDS, METHODS FOR THEIR PRODUCTION AND USE | LIGAND PHARM INC (US) | 1999-12-01 | — | — | EP | claimed |