Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 3/20 | 0.40 |
| ▸ | BRPF1 | P55201 | 3/20 | 0.38 |
| ▸ | BRD4 | O60885 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.34 |
| ▸ | PARG | Q86W56 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | BRD1 | O95696 | 1/20 | 0.34 |
| ▸ | XIAP | P98170 | 1/20 | 0.33 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8485874 | 0.80 | ALDH1A1 (0.45) | ALDH1A1KMT2AMEN1TP53LMNA | |
| SCHEMBL8489949 | 0.80 | LMNA (0.40) | BRD4LMNA | |
| SCHEMBL8488006 | 0.75 | SLC6A2 (0.44) | — | |
| SCHEMBL8488675 | 0.73 | SLC6A3 (0.41) | — | |
| SCHEMBL8487415 | 0.73 | SLC6A3 (0.43) | ALDH1A1KDM4E | |
| SCHEMBL8488165 | 0.73 | SLC6A2 (0.42) | — | |
| SCHEMBL8489089 | 0.71 | HTR2C (0.41) | — | |
| SCHEMBL8487483 | 0.70 | MDM2 (0.39) | HSD17B10TP53 | |
| SCHEMBL23411317 | 0.67 | MAPK14 (0.47) | TRIM24BRPF1BRD4ALDH1A1SMN1; SMN2 | |
| SCHEMBL8489231 | 0.66 | CHRNB2 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999038865-A1 | 8-AZABICYCLO(3.2.1)OCT-2-ENE DERIVATIVES AS PESTICIDES | ZENECA LIMITED (GB) | 1999-08-05 | — | — | WO | disclosed |