Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 3/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD5 | P21918 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8488165 | 0.84 | SLC6A2 (0.42) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL8487483 | 0.84 | MDM2 (0.39) | HTR2CMAOBSLC6A4SLC6A3HTR2A | |
| SCHEMBL8488992 | 0.75 | CHRNB2 (0.46) | — | |
| SCHEMBL8487415 | 0.74 | SLC6A3 (0.43) | DRD2SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL8485877 | 0.72 | HTR2C (0.38) | HTR2CMAOBSLC6A4SLC6A3HTR2A | |
| SCHEMBL8489231 | 0.70 | CHRNB2 (0.37) | — | |
| SCHEMBL8489949 | 0.68 | LMNA (0.40) | MAOB | |
| SCHEMBL8489583 | 0.68 | ALDH1A1 (0.41) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL8484697 | 0.68 | CHRNB2 (0.39) | — | |
| SCHEMBL11626241 | 0.66 | MAOB (0.50) | HTR2CDRD2DRD1DRD4DRD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999038865-A1 | 8-AZABICYCLO(3.2.1)OCT-2-ENE DERIVATIVES AS PESTICIDES | ZENECA LIMITED (GB) | 1999-08-05 | — | — | WO | disclosed |