Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.50 |
| ▸ | HPGD | P15428 | 7/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.50 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RHEB | Q15382 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8524420 | 0.76 | HDAC1 (0.48) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL8524729 | 0.71 | RAB9A (0.49) | ALDH1A1HPGDMAPTCYP1A2L3MBTL1 | |
| SCHEMBL18541888 | 0.68 | ALDH1A1 (0.55) | ALDH1A1KDM4EHPGDHSD17B10BRD4 | |
| SCHEMBL26705850 | 0.68 | ALDH1A1 (0.59) | ALDH1A1KDM4EHPGDHSD17B10BRD4 | |
| SCHEMBL8482201 | 0.68 | CES2 (0.51) | ALDH1A1HPGDMAPTCYP1A2L3MBTL1 | |
| SCHEMBL2445114 | 0.68 | KDM4E (1.00) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL8485994 | 0.68 | HDAC3 (0.48) | CYP1A2HDAC6 | |
| SCHEMBL8480256 | 0.66 | HDAC1 (0.56) | HPGDCYP1A2L3MBTL1HDAC6POLB | |
| SCHEMBL8484815 | 0.66 | HDAC1 (0.56) | HPGDCYP1A2L3MBTL1HDAC6POLB | |
| SCHEMBL8408930 | 0.66 | L3MBTL1 (0.56) | HPGDMAPTCYP1A2L3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5874473-A | OSTEOPOROSIS; ANTIARTHRITIC AGENTS | BAYER CORPORATION (US) | 1999-02-23 | — | — | US | disclosed |