Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8524420 | 0.79 | HDAC1 (0.48) | RAB9AALDH1A1HPGDKMT2AMAPT | |
| SCHEMBL4339780 | 0.75 | ALDH1A1 (0.56) | RAB9ANPC1ALDH1A1HPGDKMT2A | |
| SCHEMBL8482201 | 0.73 | CES2 (0.51) | ALDH1A1HPGDMAPTL3MBTL1HDAC1 | |
| SCHEMBL3867561 | 0.71 | HPGD (0.53) | RAB9ANPC1ALDH1A1HPGDMAPT | |
| SCHEMBL8480256 | 0.71 | HDAC1 (0.56) | HPGDL3MBTL1HDAC1HDAC2HDAC3 | |
| SCHEMBL8484815 | 0.71 | HDAC1 (0.56) | HPGDL3MBTL1HDAC1HDAC2HDAC3 | |
| SCHEMBL8408930 | 0.71 | L3MBTL1 (0.56) | RAB9ANPC1HPGDKMT2AMAPT | |
| SCHEMBL8525575 | 0.71 | ALDH1A1 (0.50) | ALDH1A1HPGDKMT2AMAPTL3MBTL1 | |
| SCHEMBL6278596 | 0.70 | HPGD (0.55) | RAB9ANPC1ALDH1A1HPGDMAPT | |
| SCHEMBL8408111 | 0.70 | L3MBTL1 (0.59) | RAB9ANPC1HPGDKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5874473-A | OSTEOPOROSIS; ANTIARTHRITIC AGENTS | BAYER CORPORATION (US) | 1999-02-23 | — | — | US | disclosed |