Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 1/20 | 0.52 |
| ▸ | HNF4A | P41235 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | SCN1A | P35498 | 2/20 | 0.42 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.42 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | FABP3 | P05413 | 1/20 | 0.41 |
| ▸ | FABP4 | P15090 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27410294 | 0.89 | MAPT (0.47) | BCAT2HNF4ASLC6A4SLC6A3KMT2A | |
| SCHEMBL8662843 | 0.85 | BCAT2 (0.64) | BCAT2HNF4ASLC6A4SLC6A3HTT | |
| SCHEMBL28366814 | 0.83 | BCAT2 (0.62) | BCAT2HNF4ASLC6A4SLC6A3HTT | |
| SCHEMBL23358783 | 0.82 | HNF4A (0.68) | BCAT2HNF4ASLC6A4SLC6A3HTT | |
| SCHEMBL69682 | 0.81 | SLC6A3 (0.57) | SLC6A4SLC6A3HTTKMT2AMEN1 | |
| SCHEMBL50363 | 0.79 | MAPT (0.56) | BCAT2HNF4ASLC6A3KMT2ASMN1; SMN2 | |
| SCHEMBL628030 | 0.79 | HNF4A (0.58) | BCAT2HNF4AKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL7865705 | 0.79 | HNF4A (0.53) | BCAT2HNF4ASLC6A4SLC6A3KMT2A | |
| SCHEMBL27918640 | 0.77 | HNF4A (0.44) | BCAT2HNF4ASLC6A4SLC6A3HTT | |
| SCHEMBL1348054 | 0.77 | BCAT2 (0.46) | BCAT2HNF4ASLC6A4SLC6A3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0414730-B1 | Chemical Compounds and pharmaceutical compositions capable of releasing a drug | MILLS RANDELL L (US) | 1999-12-15 | — | — | EP | claimed |