Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCZ | Q05513 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.37 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.36 |
| ▸ | BRAF | P15056 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20050668 | 0.81 | PRKCZ (0.49) | PRKCZHDAC1NOS2BRAFLMNA | |
| SCHEMBL30739840 | 0.81 | PRKCZ (0.49) | PRKCZHDAC1NOS2BRAFLMNA | |
| SCHEMBL8531602 | 0.81 | HDAC4 (0.38) | PRKCZHDAC1HDAC4HDAC6PTGS1 | |
| SCHEMBL8527965 | 0.80 | HDAC4 (0.38) | PRKCZHDAC1HDAC4HDAC6PTGS1 | |
| SCHEMBL7217875 | 0.76 | ALDH1A1 (0.50) | NR1H4MAPTHPGDGAARAB9A | |
| SCHEMBL9017625 | 0.75 | PRKCZ (0.49) | PRKCZHDAC1NOS2HSP90AB1BRAF | |
| SCHEMBL9017600 | 0.74 | PRKCZ (0.42) | PRKCZNOS2LMNAMAPTMEN1 | |
| SCHEMBL11657258 | 0.72 | PRKCZ (0.46) | PRKCZNOS2HSP90AB1LMNAMAPT | |
| SCHEMBL7219103 | 0.71 | GABRA1 (0.44) | HDAC1HDAC4HDAC6PTGS1PTGS2 | |
| SCHEMBL24252036 | 0.70 | CTSS (0.47) | PTGS1PTGS2LMNAHPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5834447-A | THIOPHENE DERIVATIVES | MONSANTO COMPANY (US) | 1998-11-10 | — | — | US | disclosed |