SCHEMBL852809

SCHEMBL852809

COC(=O)c1cc(Cl)ccc1Br

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABL1 P00519 1/20 0.59
SLC6A3 Q01959 3/20 0.51
SLC6A4 P31645 1/20 0.51
NR4A2 P43354 2/20 0.51
MAPT P10636 3/20 0.47
NPC1 O15118 2/20 0.47
RXFP1 Q9HBX9 1/20 0.47
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
LMNA P02545 3/20 0.45
ALDH1A1 P00352 2/20 0.45
KDM4E B2RXH2 1/20 0.45
F2R P25116 1/20 0.45
HTT P42858 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
ALPL P05186 1/20 0.43
NFKB1 P19838 1/20 0.43
RAB9A P51151 1/20 0.43
NFKB2 Q00653 1/20 0.43
RELA Q04206 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL610371 0.85 ABL1 (0.64) ABL1SLC6A3SLC6A4NR4A2MAPT
SCHEMBL30954389 0.83 ALDH1A1 (0.42) ABL1MAPTNPC1ALDH1A1KDM4E
SCHEMBL6100118 0.82 ABL1 (0.70) ABL1SLC6A3SLC6A4NR4A2MAPT
SCHEMBL20872668 0.82 ALDH1A1 (0.41) ABL1NR4A2MAPTNPC1KMT2A
SCHEMBL16219703 0.81 SLC6A3 (0.49) ABL1SLC6A3SLC6A4NR4A2MAPT
SCHEMBL861495 0.81 PTPN2 (0.54) SLC6A3NR4A2MAPTALDH1A1HTT
SCHEMBL4363906 0.81 ABL1 (0.62) ABL1SLC6A3SLC6A4NR4A2MAPT
SCHEMBL5096350 0.81 CYP4F2 (0.51) MAPTNPC1KMT2AKDM4EF2R
SCHEMBL2477523 0.81 CNR1 (0.42) ABL1MAPTNPC1MEN1KMT2A
SCHEMBL21102263 0.80 SLC6A3 (0.55) ABL1SLC6A3SLC6A4NR4A2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 566 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116854631-B 4-Aryl-2-pyridone compound and preparation method thereof 安徽中医药大学 2025-04-15 CN claimed
CN-116854631-A 4-aryl-2-pyridone compound and preparation method thereof 安徽中医药大学 2023-10-10 CN claimed
EP-4106028-B1 ORGANIC ELECTRONIC DEVICE COMPRISING A COMPOUND OF FORMULA (I), DISPLAY DEVICE COMPRISING THE ORGANIC ELECTRONIC DEVICE AS WELL AS COMPOUNDS OF FORMULA (I) NOVALED GMBH (DE) 2026-05-27 EP disclosed
CN-117603220-B Organic compound, organic electroluminescent device and electronic device SHAANXI LIGHTE OPTOELECTRONICS MATERIAL Co.,Ltd. (CN) 2026-05-26 CN disclosed
US-20260116868-A1 CBL-B INHIBITORS AND METHODS OF USE THEREOF ARCUS BIOSCIENCES, INC. (US) 2026-04-30 US disclosed
EP-4063466-B1 ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE INCLUDING SAME SAMSUNG SDI CO LTD (KR) 2026-04-01 EP disclosed
US-20260085067-A1 CYCLIC SULFONAMIDE RIBONUCLEOTIDE REDUCTASE (RNR) INHIBITORS AND USES THEREOF BOUNDLESS BIO INC (US) 2026-03-26 US disclosed
EP-4655296-A1 CBL-B INHIBITORS Aurigene Oncology Limited (IN) 2025-12-03 EP disclosed
EP-4356445-B1 ORGANIC ELECTRONIC DEVICE COMPRISING A COMPOUND OF FORMULA (I), DISPLAY DEVICE COMPRISING THE ORGANIC ELECTRONIC DEVICE AS WELL AS COMPOUNDS OF FORMULA (I) NOVALED GMBH (DE) 2025-10-08 EP disclosed
US-12433152-B2 Compound for organic optoelectronic device, composition for organic optoelectronic device, organic optoelectronic device and display device SAMSUNG SDI CO., LTD. (KR) 2025-09-30 US disclosed
EP-4605409-A2 CYCLIN INHIBITORS Circle Pharma, Inc. (US) 2025-08-27 EP disclosed
WO-2002050056-A1 BENZYLAMINE DERIVATIVES AND THEIR USE AS THROMBIN INHIBITORS MERCK & CO., INC. (US) 2002-06-27 WO disclosed
US-5428033-A Useful as anti-asthmatic, anti-allergic, anti-inflammatory and cytoprotecyive agents MERCK FROSST CANADA, INC. (CA) 1995-06-27 US disclosed
EP-0137333-B1 SPIRO-TRICYCLICAROMATIC SUCCINIMIDE DERIVATIVES AS INHIBITORS OF ALDOSE REDUCTASE ALCON LABORATORIES, INC. (US) 1992-12-30 EP disclosed
US-5153211-A Enzyme inhibitors ALCON LABORATORIES, INC. (US) 1992-10-06 US disclosed
CN-1061408-A Saturated hydroxyalkyl quinolinic acids as leukotriene antagonists MERCK FROSST CANADA INC (US) 1992-05-27 CN disclosed
EP-0480716-A1 Saturated hydroxyalkylquinoline acids as leukotriene antagonists MERCK FROSST CANADA INC. (CA) 1992-04-15 EP disclosed
US-5070100-A COMPLICATIONS OF DIABETES ALCON LABORATORIES, INC. (US) 1991-12-03 US disclosed
US-4864028-A ANTIDIABETIC AGENTS ALCON LABORATORIES, INC. (US) 1989-09-05 US disclosed
US-4537892-A ANTIDIABETIC AGENTS ALCON LABORATORIES, INC. (US) 1985-08-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260085067-A1 CYCLIC SULFONAMIDE RIBONUCLEOTIDE REDUCTASE (RNR) INHIBITORS AND USES THEREOF RRM1, RRM2B, RRM2 ABL1 3090/4885SLC6A3 566/4885SLC6A4 1229/4885
US-20260116868-A1 CBL-B INHIBITORS AND METHODS OF USE THEREOF CBLB, CBLC, CBL ABL1 15/4885SLC6A3 1884/4885SLC6A4 2678/4885
US-12433152-B2 Compound for organic optoelectronic device, composition for organic optoelectronic device, organic optoelectronic device and display device OCIAD2, OCIAD1, OXER1 ABL1 2099/4885SLC6A3 3306/4885SLC6A4 4443/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.