Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 7/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2687430 | 0.81 | GSK3B (0.40) | SMN1; SMN2HTR6ALDH1A1LMNAMAPT | |
| SCHEMBL1791418 | 0.79 | SMN1; SMN2 (0.50) | SMN1; SMN2HTR6ALDH1A1TSHRMAPK1 | |
| SCHEMBL6069944 | 0.77 | CA2 (0.50) | SMN1; SMN2HTR6ALDH1A1PKMCA12 | |
| SCHEMBL28078917 | 0.77 | TRPV4 (0.47) | SMN1; SMN2HTR6NFE2L2NPC1ALDH1A1 | |
| SCHEMBL5248910 | 0.75 | HTR6 (0.55) | HTR6NFE2L2NPC1TSHRKCNH2 | |
| SCHEMBL9809420 | 0.74 | TDP1 (0.33) | SMN1; SMN2NPC1ALDH1A1LMNATP53 | |
| SCHEMBL28699989 | 0.72 | HTR6 (0.65) | HTR6ALDH1A1TP53HSD17B10PKM | |
| SCHEMBL11327832 | 0.71 | L3MBTL1 (0.58) | SMN1; SMN2ALDH1A1LMNATP53MAPT | |
| SCHEMBL10405334 | 0.70 | ALDH1A1 (0.37) | SMN1; SMN2HTR6ALDH1A1LMNATP53 | |
| SCHEMBL6069951 | 0.70 | CA2 (0.46) | ALDH1A1PKMCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0629666-B1 | Water-soluble azo compounds, process for their preparation and their use as dyestuffs | DYSTAR TEXTILFARBEN GMBH & CO (DE) | 1998-12-02 | — | — | EP | disclosed |
| US-5548072-A | FOR WOOL, POLYAMIDES, CELLULOSE AND COTTON | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-08-20 | — | — | US | disclosed |
| EP-0629666-A1 | Water-soluble azo compounds, process for their preparation and their use as dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-12-21 | — | — | EP | disclosed |
| EP-0377166-B1 | Water-soluble, fibre-reactive dyes, methods for their preparation and their use | HOECHST AG (DE) | 1994-03-02 | — | — | EP | disclosed |
| US-5138041-A | Water-soluble fiber-reactive monoazo and disazo dyestuffs having a s-triazinylamino group and three fiber-reactive groups of the vinylsulfone series | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-08-11 | — | — | US | disclosed |
| EP-0377166-A1 | Water-soluble, fibre-reactive dyes, methods for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-07-11 | — | — | EP | disclosed |