Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | SI | P14410 | 1/20 | 0.35 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2397583 | 0.81 | CYP1A2 (0.45) | L3MBTL1KMT2APOLBCYP1A2GAA | |
| SCHEMBL8532811 | 0.80 | L3MBTL1 (0.35) | L3MBTL1KMT2APOLBCYP1A2GAA | |
| SCHEMBL27622392 | 0.77 | L3MBTL1 (0.49) | L3MBTL1KMT2APOLBCYP1A2GAA | |
| SCHEMBL4036129 | 0.77 | L3MBTL1 (0.49) | L3MBTL1KMT2APOLBCYP1A2GAA | |
| SCHEMBL10406964 | 0.77 | L3MBTL1 (0.49) | L3MBTL1KMT2APOLBCYP1A2GAA | |
| SCHEMBL11656058 | 0.76 | KMT2A (0.46) | L3MBTL1KMT2APOLBCYP1A2GAA | |
| SCHEMBL11652884 | 0.75 | GABRP (0.48) | L3MBTL1KMT2APOLBCYP1A2GAA | |
| SCHEMBL18561876 | 0.75 | L3MBTL1 (0.50) | L3MBTL1KMT2APOLBCYP1A2GAA | |
| SCHEMBL8410329 | 0.75 | L3MBTL1 (0.50) | L3MBTL1KMT2APOLBCYP1A2GAA | |
| SCHEMBL8410331 | 0.75 | L3MBTL1 (0.50) | L3MBTL1KMT2APOLBCYP1A2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773428-A | BONE DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1998-06-30 | — | — | US | disclosed |
| EP-0807114-A1 | BRIDGED INDOLES AS MATRIX METALLOPROTEASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1997-11-19 | — | — | EP | disclosed |
| EP-0726903-B1 | MATRIX METALLOPROTEASE INHIBITORS | SYNTEX INC (US) | 1997-07-16 | — | — | EP | disclosed |