Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 7/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 2/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | JUN | P05412 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5156363 | 0.81 | TBXAS1 (0.61) | TBXAS1CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL5156355 | 0.81 | TBXAS1 (0.61) | TBXAS1CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL8527896 | 0.74 | CHRNB2 (0.42) | TBXAS1CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL9732341 | 0.73 | TBXAS1 (0.68) | TBXAS1CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL9732343 | 0.73 | TBXAS1 (0.68) | TBXAS1CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL29210240 | 0.71 | L3MBTL1 (0.48) | CYP2C9CYP2C19PPARGMAPT | |
| SCHEMBL507379 | 0.69 | SMN1; SMN2 (0.51) | RAB9A | |
| SCHEMBL9843054 | 0.69 | TBXAS1 (0.47) | TBXAS1CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL9843049 | 0.69 | TBXAS1 (0.47) | TBXAS1CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL9732628 | 0.67 | TBXAS1 (0.56) | TBXAS1CHRNB2CHRNA4CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849922-A | Preparation of substituted alkenoic acids | ELI LILLY AND COMPANY (US) | 1998-12-15 | — | — | US | disclosed |