Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.32 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.30 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.30 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.30 |
| ▸ | LCK | P06239 | 1/20 | 0.30 |
| ▸ | FYN | P06241 | 1/20 | 0.30 |
| ▸ | DAO | P14920 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8528407 | 0.81 | PTPN1 (0.41) | FOLH1 | |
| SCHEMBL8531845 | 0.78 | MEN1 (0.38) | FOLH1 | |
| SCHEMBL8529423 | 0.78 | KIF11 (0.38) | FOLH1 | |
| SCHEMBL8528404 | 0.76 | FDPS (0.38) | — | |
| SCHEMBL8529288 | 0.75 | PTPN5 (0.43) | — | |
| SCHEMBL8532194 | 0.75 | FDPS (0.45) | — | |
| SCHEMBL8530829 | 0.75 | ALDH1A1 (0.40) | — | |
| SCHEMBL8532545 | 0.75 | KIF11 (0.40) | FOLH1 | |
| SCHEMBL8531385 | 0.74 | GRM4 (0.39) | SLC1A2 | |
| SCHEMBL8528037 | 0.74 | SLC1A3 (0.36) | FOLH1SLC1A3SLC1A2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0752999-B1 | 2,4-DIPHOSPHONOGLUTARIC ACID DERIVATIVES, METHODS OF PREPARING SUCH COMPOUNDS AND DRUGS CONTAINING THEM | BOEHRINGER MANNHEIM GMBH (DE) | 1998-10-28 | — | — | EP | disclosed |
| US-5698541-A | DISEASES OF CALCIUM METABOLISM; OSTEOPOROSIS | BOEHRINGER MANNHEIM GMBH (DE) | 1997-12-16 | — | — | US | disclosed |