Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8535968 | 0.91 | NPC1 (0.37) | CA2CA4SMN1; SMN2NPC1 | |
| SCHEMBL8538467 | 0.80 | PPARG (0.37) | KDM4EL3MBTL1CA2HPGDHSD17B10 | |
| SCHEMBL8535732 | 0.78 | KDM4E (0.39) | KDM4ETDP1L3MBTL1LMNAHPGD | |
| SCHEMBL8534507 | 0.74 | KDM4E (0.40) | KDM4ETSHRPKML3MBTL1LMNA | |
| SCHEMBL6965449 | 0.72 | PTGER4 (0.39) | KDM4ETSHRLMNAHPGDNPSR1 | |
| SCHEMBL8533753 | 0.72 | KDM4E (0.34) | KDM4ETSHRTDP1PKML3MBTL1 | |
| SCHEMBL9039893 | 0.71 | LMNA (0.43) | KDM4ETSHRTDP1L3MBTL1LMNA | |
| SCHEMBL11787842 | 0.69 | ALDH1A1 (0.45) | KDM4ETDP1CA2HPGDKMT2A | |
| SCHEMBL8538683 | 0.68 | KMT2A (0.39) | KDM4EL3MBTL1CA2LMNAHPGD | |
| SCHEMBL6952662 | 0.67 | PTPN7 (0.47) | LMNAHPGDKMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5808062-A | AIDS THERAPY | WARNER-LAMBERT COMPANY (US) | 1998-09-15 | — | — | US | claimed |
| US-5808062-A | AIDS THERAPY | WARNER-LAMBERT COMPANY (US) | 1998-09-15 | — | — | US | disclosed |