Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | MMP2 | P08253 | 10/20 | 0.45 |
| ▸ | MMP9 | P14780 | 9/20 | 0.45 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.45 |
| ▸ | F10 | P00742 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | MMP7 | P09237 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | PLG | P00747 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7449163 | 0.86 | F2 (0.48) | F10POLBPLG | |
| SCHEMBL8086169 | 0.79 | GNPAT (0.44) | ALDH1A1 | |
| SCHEMBL31086837 | 0.77 | ALDH1A1 (1.00) | ALDH1A1MAPTMMP2MMP9ADAMTS4 | |
| SCHEMBL7436890 | 0.75 | ALPI (0.44) | — | |
| SCHEMBL7451264 | 0.75 | FAAH (0.43) | ALDH1A1 | |
| SCHEMBL8089807 | 0.75 | CTSK (0.54) | ALDH1A1 | |
| SCHEMBL7441597 | 0.75 | CTSK (0.54) | ALDH1A1 | |
| SCHEMBL8533828 | 0.74 | ALDH1A1 (0.61) | ALDH1A1MAPTMMP2MMP9ADAMTS4 | |
| SCHEMBL7438536 | 0.73 | NOS2 (0.48) | ALDH1A1MAPTCYP3A4 | |
| SCHEMBL31086912 | 0.72 | ALDH1A1 (0.80) | ALDH1A1MAPTMMP2MMP9ADAMTS4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5986108-A | ENZYME INHIBITORS | SYNPHAR LABORATORIES, INC. (CA) | 1999-11-16 | — | — | US | disclosed |