Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | TACR1 | P25103 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8530490 | 0.82 | NOTUM (0.46) | TSHRLMNARAB9AMAPTNPSR1 | |
| SCHEMBL8530972 | 0.81 | TSHR (0.52) | TSHRLMNAHSD17B10RAB9AMAPT | |
| SCHEMBL28107171 | 0.77 | LMNA (0.76) | TSHRLMNAHSD17B10RAB9AMAPT | |
| SCHEMBL8530555 | 0.75 | TACR1 (0.46) | MAPTALDH1A1TACR1 | |
| SCHEMBL890039 | 0.73 | LMNA (0.77) | TSHRLMNAHSD17B10RAB9AMAPT | |
| Hydrochloric Acid SCHEMBL5459649 | 0.72 | L3MBTL1 (0.73) | TSHRLMNAHSD17B10RAB9AMAPT | |
| Hydrochloric Acid SCHEMBL5466223 | 0.72 | ALDH1A1 (0.85) | TSHRLMNAHSD17B10RAB9AMAPT | |
| SCHEMBL28107112 | 0.72 | ALDH1A1 (0.68) | TSHRLMNAHSD17B10RAB9AMAPT | |
| Bromide SCHEMBL28098177 | 0.71 | LMNA (0.74) | TSHRLMNAHSD17B10RAB9AMAPT | |
| Hydrochloric Acid SCHEMBL7981337 | 0.71 | LMNA (0.74) | TSHRLMNAHSD17B10RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5843966-A | Piperidine derivatives | GLAXO GROUP LIMITED (GB) | 1998-12-01 | — | — | US | disclosed |