Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 4/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8531726 | 0.86 | WDR5 (0.32) | DHODHCASP1 | |
| SCHEMBL8532207 | 0.74 | CA1 (0.33) | — | |
| SCHEMBL6777725 | 0.66 | RAB9A (0.50) | — | |
| SCHEMBL8531518 | 0.66 | CA1 (0.34) | — | |
| SCHEMBL8532447 | 0.64 | PTGS1 (0.40) | DHODHTP53 | |
| SCHEMBL7373859 | 0.64 | GPR132 (0.53) | — | |
| SCHEMBL7376317 | 0.64 | GPR132 (0.49) | — | |
| SCHEMBL7376324 | 0.64 | GPR132 (0.49) | — | |
| SCHEMBL7375387 | 0.64 | GPR132 (0.42) | — | |
| SCHEMBL8429467 | 0.64 | CYP1A2 (0.41) | CASP1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773646-A | INTEGRIN INHIBITORS | G. D. SEARLE & CO. (US) | 1998-06-30 | — | — | US | disclosed |