Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 2/20 | 0.44 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TRPV4 | Q9HBA0 | 3/20 | 0.42 |
| ▸ | KIF11 | P52732 | 2/20 | 0.40 |
| ▸ | CTSV | O60911 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.39 |
| ▸ | TUBB | P07437 | 1/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.39 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.39 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.39 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.39 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8535103 | 0.93 | TUBB4A (0.48) | IMPDH2MAP4K1ALDH1A1MEN1KMT2A | |
| SCHEMBL8538008 | 0.78 | CTSV (0.63) | ALDH1A1MEN1KMT2AKIF11CTSV | |
| SCHEMBL8535774 | 0.77 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2ACTSVCTSL | |
| SCHEMBL8537802 | 0.76 | KDM4E (0.44) | ALDH1A1MEN1KMT2ACTSVCTSL | |
| SCHEMBL8531701 | 0.74 | ALDH1A1 (0.57) | IMPDH2ALDH1A1MEN1KMT2ACTSV | |
| SCHEMBL20983235 | 0.73 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2ACTSVCTSL | |
| SCHEMBL26847003 | 0.70 | HPGD (0.68) | ALDH1A1MEN1KMT2AKIF11CTSV | |
| SCHEMBL10275605 | 0.70 | IMPDH2 (0.49) | IMPDH2ALDH1A1MEN1KMT2AKIF11 | |
| SCHEMBL2056171 | 0.69 | ALDH1A1 (0.59) | MAP4K1ALDH1A1MEN1KMT2ATRPV4 | |
| SCHEMBL28977195 | 0.68 | MELK (0.69) | MAP4K1ALDH1A1TRPV4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012069856-A1 | ANTIMALARIAL COMPOUNDS | LIVERPOOL SCHOOL OF TROPICAL MEDICINE (GB) | 2012-05-31 | — | — | WO | claimed |
| WO-2012069856-A1 | ANTIMALARIAL COMPOUNDS | LIVERPOOL SCHOOL OF TROPICAL MEDICINE (GB) | 2012-05-31 | — | — | WO | disclosed |