Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 3/20 | 0.39 |
| ▸ | MMP2 | P08253 | 3/20 | 0.39 |
| ▸ | MMP9 | P14780 | 3/20 | 0.39 |
| ▸ | MMP12 | P39900 | 3/20 | 0.39 |
| ▸ | MMP13 | P45452 | 3/20 | 0.39 |
| ▸ | MMP14 | P50281 | 3/20 | 0.39 |
| ▸ | MMP3 | P08254 | 2/20 | 0.39 |
| ▸ | ALB | P02768 | 1/20 | 0.39 |
| ▸ | BCL2 | P10415 | 2/20 | 0.37 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.37 |
| ▸ | HPN | P05981 | 2/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.37 |
| ▸ | ABCC9 | O60706 | 5/20 | 0.36 |
| ▸ | ABCC8 | Q09428 | 5/20 | 0.36 |
| ▸ | KCNJ11 | Q14654 | 5/20 | 0.36 |
| ▸ | KCNJ8 | Q15842 | 5/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8534198 | 0.78 | LMNA (0.40) | ITGB3MEN1KMT2ALMNACA12 | |
| SCHEMBL8532987 | 0.77 | ITGB3 (0.38) | ITGB3MEN1KMT2ALMNACA12 | |
| SCHEMBL7862025 | 0.72 | TSHR (0.52) | ABCC9ABCC8KCNJ11KCNJ8MEN1 | |
| SCHEMBL7862023 | 0.71 | CA2 (0.39) | HPNPLAUITGB3ITGA2BALDH1A1 | |
| SCHEMBL8534686 | 0.69 | FEN1 (0.44) | ITGB3MEN1KMT2ALMNACA12 | |
| SCHEMBL8532235 | 0.67 | CA1 (0.40) | ITGB3MEN1TSHRKMT2AALDH1A1 | |
| SCHEMBL8561074 | 0.67 | NAMPT (0.50) | MMP1MMP2MMP9MMP12MMP13 | |
| SCHEMBL2838666 | 0.67 | KMT2A (0.48) | MMP2MMP3HPNPLAUITGB3 | |
| SCHEMBL8431256 | 0.67 | CASR (0.38) | ITGB3ITGA2B | |
| SCHEMBL8534236 | 0.67 | CA1 (0.40) | LMNACA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773646-A | INTEGRIN INHIBITORS | G. D. SEARLE & CO. (US) | 1998-06-30 | — | — | US | disclosed |