Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 4/20 | 0.48 |
| ▸ | MMP2 | P08253 | 4/20 | 0.48 |
| ▸ | MMP9 | P14780 | 4/20 | 0.48 |
| ▸ | MMP3 | P08254 | 4/20 | 0.48 |
| ▸ | MMP13 | P45452 | 4/20 | 0.48 |
| ▸ | MMP7 | P09237 | 1/20 | 0.48 |
| ▸ | MMP14 | P50281 | 1/20 | 0.48 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7629106 | 0.89 | MMP1 (0.61) | MMP1MMP2MMP9MMP3MMP13 | |
| SCHEMBL6763693 | 0.89 | MMP1 (0.61) | MMP1MMP2MMP9MMP3MMP13 | |
| SCHEMBL7604548 | 0.78 | MMP3 (0.63) | MMP1MMP2MMP9MMP3MMP13 | |
| SCHEMBL7606336 | 0.77 | MMP1 (0.77) | MMP1MMP2MMP9MMP3MMP13 | |
| SCHEMBL7887186 | 0.74 | MMP1 (0.42) | MMP1MMP2MMP9MMP3MMP13 | |
| SCHEMBL6554500 | 0.71 | MMP2 (0.64) | MMP1MMP2MMP9MMP3MMP13 | |
| SCHEMBL7608470 | 0.68 | MMP2 (0.40) | MMP1MMP2MMP9MMP3MMP13 | |
| SCHEMBL6555661 | 0.68 | MMP1 (0.78) | MMP1MMP2MMP9MMP3MMP13 | |
| SCHEMBL6760102 | 0.68 | MMP3 (0.81) | MMP1MMP2MMP9MMP3MMP13 | |
| SCHEMBL6766456 | 0.66 | MMP1 (0.67) | MMP1MMP2MMP9MMP3MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5981490-A | ADMINISTERING A PEPTIDYL COMPOUND FOR TREATMENT IN A HUMAN OR ANIMAL OF A CONDITION ASSOCIATED WITH MATRIX METALIOPROTEINASES OR THAT IS MEDIATED BY TUMOR NECROSIS FACTOR ALPHA OR L-SELECTIN SHEDDASE | DARWIN DISCOVERY, LTD. (GB) | 1999-11-09 | — | — | US | disclosed |