SCHEMBL8535668

SCHEMBL8535668

CC(=O)N(C)c1cccnc1S(=O)(=O)Cl

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSPO P30536 1/20 0.39
FSCN1 Q16658 1/20 0.38
ALDH1A1 P00352 3/20 0.37
SMN1; SMN2 Q16637 3/20 0.37
KDM4E B2RXH2 1/20 0.37
MAPT P10636 1/20 0.36
HSD17B1 P14061 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
NPC1 O15118 1/20 0.33
TP53 P04637 1/20 0.33
MAPK1 P28482 1/20 0.33
RAB9A P51151 1/20 0.33
STS P08842 1/20 0.33
KMT2A Q03164 2/20 0.33
MEN1 O00255 1/20 0.33
HSD17B10 Q99714 1/20 0.33
GAA P10253 1/20 0.33
RXFP1 Q9HBX9 1/20 0.32
S100A4 P26447 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7955241 0.84 TSPO (0.39) TSPOFSCN1ALDH1A1SMN1; SMN2KDM4E
SCHEMBL9244018 0.73 SMN1; SMN2 (0.40) ALDH1A1SMN1; SMN2KDM4EMAPTKMT2A
SCHEMBL30151488 0.73 SMN1; SMN2 (0.40) ALDH1A1SMN1; SMN2KDM4EMAPTKMT2A
SCHEMBL22072300 0.71 LMNA (0.49) ALDH1A1SMN1; SMN2KDM4EMAPTNPC1
SCHEMBL26666368 0.70 ALDH1A1 (0.40) TSPOFSCN1ALDH1A1SMN1; SMN2KDM4E
SCHEMBL8539682 0.69 FFAR4 (0.42) TSPOFSCN1ALDH1A1SMN1; SMN2KDM4E
SCHEMBL27480726 0.69 ADRA1D (0.43) ALDH1A1SMN1; SMN2KDM4ENPC1RAB9A
SCHEMBL1039344 0.69 NOS3 (0.43) ALDH1A1SMN1; SMN2KDM4ENPC1RAB9A
SCHEMBL9826240 0.68 LMNA (0.56) ALDH1A1SMN1; SMN2KDM4EMAPTCYP2C9
SCHEMBL30299648 0.67 ALDH1A1 (0.45) TSPOFSCN1ALDH1A1SMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0600836-B1 Selective herbicidal agent CIBA GEIGY AG (CH) 1998-08-05 EP disclosed
US-5612288-A PYRIDYLSULFONYLUREAS AS PLANT HERBICIDES CIBA GEIGY CORPORATION (US) 1997-03-18 US disclosed
US-5532203-A SULFONYLUREA MIXTURE CIBA-GEIGY CORPORATION (US) 1996-07-02 US disclosed
EP-0600836-A2 Selective herbicidal agent CIBA-GEIGY AG (CH) 1994-06-08 EP disclosed