SCHEMBL7955241

SCHEMBL7955241

CC(=O)N(C)c1cccnc1S(N)(=O)=O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSPO P30536 1/20 0.39
STS P08842 1/20 0.37
ALDH1A1 P00352 2/20 0.37
KDM4E B2RXH2 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
FTO Q9C0B1 1/20 0.36
CA2 P00918 4/20 0.35
CA1 P00915 3/20 0.35
CA9 Q16790 3/20 0.35
MAPK1 P28482 1/20 0.35
FSCN1 Q16658 1/20 0.35
KMT2A Q03164 2/20 0.35
HSD17B1 P14061 1/20 0.34
CA12 O43570 2/20 0.34
CA5A P35218 2/20 0.34
CA5B Q9Y2D0 2/20 0.34
P2RX7 Q99572 1/20 0.34
CYP2C9 P11712 2/20 0.34
CYP2C19 P33261 1/20 0.34
HSD17B10 Q99714 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8535668 0.84 TSPO (0.39) TSPOSTSALDH1A1KDM4ESMN1; SMN2
SCHEMBL8121926 0.78 KMT2A (0.42) FTOCA2CA1CA9MAPK1
SCHEMBL2705046 0.73 P2RX7 (0.41) ALDH1A1KDM4ESMN1; SMN2FTOCA2
SCHEMBL8874470 0.73 CA2 (0.33) FTOCA2CA1CA9MAPK1
SCHEMBL22072300 0.71 LMNA (0.49) ALDH1A1KDM4ESMN1; SMN2HSD17B10CYP3A4
SCHEMBL8537341 0.70 FTO (0.49) ALDH1A1KDM4EFTOCA2CA1
SCHEMBL27299205 0.70 KDM4E (0.46) ALDH1A1KDM4EFTOCA2CA1
SCHEMBL26666368 0.70 ALDH1A1 (0.40) TSPOALDH1A1KDM4ESMN1; SMN2FSCN1
SCHEMBL8539682 0.69 FFAR4 (0.42) TSPOALDH1A1KDM4ESMN1; SMN2FSCN1
SCHEMBL9363330 0.69 ADRA1D (0.43) ALDH1A1KDM4ESMN1; SMN2KMT2AP2RX7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6316388-B1 ANTIGROWTH AGENTS FOR PLANTS HOECHST SCHERING AGREVO GMBH (DE) 2001-11-13 US disclosed
US-5847146-A N-heteroartyl-n'-(pyrid-2yl-sulfonyl) ureas, processes for their preparation, and their use as herbicides and plant growth regulators HOECHST SCHERING AGREVO GMBH (DE) 1998-12-08 US disclosed
EP-0600836-B1 Selective herbicidal agent CIBA GEIGY AG (CH) 1998-08-05 EP disclosed
US-5612288-A PYRIDYLSULFONYLUREAS AS PLANT HERBICIDES CIBA GEIGY CORPORATION (US) 1997-03-18 US disclosed
US-5532203-A SULFONYLUREA MIXTURE CIBA-GEIGY CORPORATION (US) 1996-07-02 US disclosed
US-5371060-A PREFERENTIAL WEED CONTROL CIBA-GEIGY CORPORATION (US) 1994-12-06 US disclosed
EP-0600836-A2 Selective herbicidal agent CIBA-GEIGY AG (CH) 1994-06-08 EP disclosed
EP-0558448-A1 1,5-diphenylpyrazole-3-carboxylic acid derivatives as antidotes for sulfonylurea herbicides CIBA-GEIGY AG (CH) 1993-09-01 EP disclosed
EP-0555770-A1 N-Heteroaryl-N'-(pyrid-2-yl-sulfonyl)-ureas, process for their preparation, and their use as herbicides and plant growth regulators Hoechst Schering AgrEvo GmbH (DE) 1993-08-18 EP disclosed