Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 6/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.39 |
| ▸ | SHBG | P04278 | 1/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 6/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.35 |
| ▸ | CYP21A2 | P08686 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | STS | P08842 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8542953 | 0.75 | PGR (0.42) | PGRCYP1B1CYP17A1CYP19A1CYP21A2 | |
| SCHEMBL8542951 | 0.74 | PGR (0.41) | PGRCYP1B1CYP17A1CYP19A1CYP21A2 | |
| SCHEMBL10667745 | 0.72 | SHBG (0.44) | PGRSHBGCYP19A1STS | |
| SCHEMBL7577119 | 0.68 | ESR1 (0.57) | PGRSHBGCYP19A1STS | |
| SCHEMBL10380828 | 0.66 | CYP19A1 (0.51) | CYP17A1CYP19A1CYP21A2 | |
| SCHEMBL9839177 | 0.65 | SHBG (0.42) | PGRSHBGCYP19A1STS | |
| SCHEMBL8538439 | 0.65 | CYP19A1 (0.35) | PGRSHBGCYP19A1STS | |
| SCHEMBL8539487 | 0.64 | ESR1 (0.42) | PGRCYP1B1SHBGSTS | |
| SCHEMBL6577539 | 0.63 | SHBG (0.49) | PGRSHBGCYP19A1STS | |
| SCHEMBL8538436 | 0.63 | CYP19A1 (0.35) | PGRSHBGCYP17A1CYP19A1STS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5843933-A | 11β-aryl-4-estrenes, process for their production as well as their use as pharmaceutical agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-12-01 | — | — | US | disclosed |
| US-5728689-A | ANTIGESTAGENIC EFFECT | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-03-17 | — | — | US | disclosed |