Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8537740 | 0.84 | ADRA2A (0.48) | ADRA2AADRA1AADRB2ADRB1ADRB3 | |
| SCHEMBL7784230 | 0.83 | ADRA1A (0.45) | ADRA2AADRA1AGRIN2BHTR2ASLC6A4 | |
| SCHEMBL8538491 | 0.81 | PDE5A (0.36) | ADRA1AADRB2ADRB1 | |
| SCHEMBL11552416 | 0.77 | ACLY (0.40) | PPARG | |
| SCHEMBL9266828 | 0.76 | ADRA2C (0.51) | GAA | |
| SCHEMBL8536545 | 0.76 | TBXAS1 (0.40) | ADRA2AADRA1AGAA | |
| SCHEMBL8540406 | 0.75 | AOC3 (0.51) | GRIN2BGAAGSK3B | |
| SCHEMBL11385852 | 0.73 | SLC6A4 (0.42) | ADRA2AADRA1AHTR2ASLC6A4KCNH2 | |
| SCHEMBL474013 | 0.73 | PDE2A (0.51) | ADRA2AADRA1AHTR2ASLC6A4KCNH2 | |
| SCHEMBL8537569 | 0.72 | MAPT (0.53) | SLC6A4GAAMRGPRX4PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750532-A | TETRAHYDROPYRIMIDINE-2,4-DIONE DERIVATIVES, VIRICIDES, ANTIINFLAMMATORY AGENTS, PAF INHIBITORS | SCHERING CORPORATION (US) | 1998-05-12 | — | — | US | disclosed |