Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | PPID | Q08752 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8540442 | 0.85 | ALDH1A1 (0.53) | ADAM17SMN1; SMN2EPHX2ALDH1A1 | |
| SCHEMBL8543401 | 0.82 | USP2 (0.47) | POLBADAM17SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL8543060 | 0.81 | ADAM17 (0.45) | ADAM17SMN1; SMN2CYP3A4CYP2C9PKM | |
| SCHEMBL8542792 | 0.81 | OPRM1 (0.54) | MAPK1SMN1; SMN2 | |
| SCHEMBL8541500 | 0.77 | ACHE (0.43) | MAPK1SMN1; SMN2ALDH1A1MAPTHPGD | |
| SCHEMBL8537772 | 0.76 | ALDH1A1 (0.47) | ADAM17SMN1; SMN2CYP3A4CYP2C9ALDH1A1 | |
| SCHEMBL8539067 | 0.76 | HTR1A (0.50) | ALDH1A1LMNA | |
| SCHEMBL8539767 | 0.76 | ALDH1A1 (0.46) | ADAM17ALDH1A1 | |
| SCHEMBL8539332 | 0.75 | KDM4E (0.53) | POLBADAM17SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL8541234 | 0.75 | ADAM17 (0.53) | ADAM17EPHX2PPID |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0671388-B1 | (Pyrrolidinyl)phenyl carbamates and intermediate compounds, processes for their preparation and their use as medicaments | HOECHST MARION ROUSSEL INC (US) | 1998-06-10 | — | — | EP | claimed |